1. Mirroring Life's Building Blocks
- Author
-
Ashraf Brik and Roman Meledin
- Subjects
Pharmacology ,010405 organic chemistry ,Clinical Biochemistry ,Chemical biology ,Proteins ,Computational biology ,DNA ,Biology ,01 natural sciences ,Biochemistry ,Chemical synthesis ,0104 chemical sciences ,Living systems ,Ligases ,Artificial life ,Drug Discovery ,Molecular Medicine ,Amino Acids ,Molecular Biology ,Mirroring - Abstract
Preparation of proteins composed entirely of D-amino acids is an elegant approach to assemble completely orthogonal living systems. In this issue of Cell Chemical Biology, Weidmann et al. (2019) demonstrate the chemical synthesis and characterization of mirror image DNA-ligase, which represents an important step for the creation of artificial life.
- Published
- 2019