1. A Conserved Mito-Cytosolic Translational Balance Links Two Longevity Pathways
- Author
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Michel van Weeghel, Sylvie Rabot, Jiayi Lan, Marco Lezzerini, Aldo Jongejan, Ruedi Aebersold, Perry D. Moerland, Georges E. Janssens, Evan G. Williams, Fatima Joly, Mark A. McCormick, Marte Molenaars, Alyson W. MacInnes, Riekelt H. Houtkooper, Antoine H. C. van Kampen, Brian K. Kennedy, Bauke V. Schomakers, Yasmine J. Liu, Graduate School, AGEM - Endocrinology, metabolism and nutrition, AGEM - Inborn errors of metabolism, Laboratory for General Clinical Chemistry, AGEM - Amsterdam Gastroenterology Endocrinology Metabolism, Epidemiology and Data Science, APH - Methodology, Laboratory Genetic Metabolic Diseases, APH - Personalized Medicine, APH - Aging & Later Life, ACS - Diabetes & metabolism, and ACS - Heart failure & arrhythmias
- Subjects
0301 basic medicine ,cytosolic translation ,Ribosomal Proteins ,Translational efficiency ,Proteome ,Physiology ,Mitochondrial translation ,translational balance ,Longevity ,Mitochondrion ,Biology ,mitochondrial translation ,Article ,ribosomes ,Transcriptome ,03 medical and health sciences ,0302 clinical medicine ,Cytosol ,longevity ,Ribosomal protein ,RNA interference ,Stress, Physiological ,Animals ,ATF4 ,Caenorhabditis elegans ,Caenorhabditis elegans Proteins ,Molecular Biology ,Psychological repression ,doxycycline ,aging ,Translation (biology) ,Cell Biology ,Cell biology ,Mitochondria ,Up-Regulation ,Mice, Inbred C57BL ,030104 developmental biology ,translational efficiency ,Phenotype ,Doxycycline ,Protein Biosynthesis ,RNA Interference ,Genetics & genetic processes [F10] [Life sciences] ,polysome ,Génétique & processus génétiques [F10] [Sciences du vivant] ,030217 neurology & neurosurgery ,Signal Transduction ,Transcription Factors - Abstract
Cell Metabolism, 31 (3), ISSN:1550-4131, ISSN:1932-7420
- Published
- 2018