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1. Pancreatic plasticity: Unlocking exocrine lineage specification.

Author

Pitarresi JR and Rustgi AK

Subjects
Acinar Cells, Humans, Organoids, Pancreas, Pancreatic Ducts, Pancreas, Exocrine, Pancreatic Neoplasms, Pluripotent Stem Cells
Abstract

In this issue of Cell Stem Cell, Huang et al. (2021) and Breunig et al. (2021) developed human stem-cell-derived organoid culture systems to recapitulate pancreatic acinar and ductal lineages. This provides opportunities to study cellular plasticity and transformation in pancreatic cancer initiation and progression., (Copyright © 2021 Elsevier Inc. All rights reserved.)

Published
2021
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