1. Mesenchymal Stromal Cells "Think" Globally, but Act Locally.
- Author
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Eissner, Günther
- Subjects
STROMAL cells ,WOUND healing ,MONONUCLEAR leukocytes ,REGULATORY T cells ,CORD blood ,T helper cells - Abstract
In this Special Issue of I Cells i , entitled "Immunomodulation by Mesenchymal Stem Cells 2020", you can find five excellent papers on the role of mesenchymal stem/stromal cells (MSCs) in immunomodulation, which also includes regenerative processes, such as wound healing. Although the precise mechanism of action (MOA) of these cells in various clinical applications is not fully understood, recent progress has been made in the functional characterisation of MSCs and their extracellular vesicles, especially in the perinatal field [[3], [5]], which can easily been translated to adult MSCs. 10.3390/cells10020280 9 Fiori A., Uhlig S., Kluter H., Bieback K. Human Adipose Tissue-Derived Mesenchymal Stromal Cells Inhibit CD4+ T Cell Proliferation and Induce Regulatory T Cells as Well as CD127 Expression on CD4+CD25+ T Cells. [Extracted from the article]
- Published
- 2023
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