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In order to improve antibacterial capability and cell biocompatibility of titanium (Ti), Ag nanoparticles (NPs) and a novel Zn source Na 2 Zn-EDTA (disodium zinc ethylenediaminetetraacetate tetrahydrate) were added in the electrolyte to fabricate Ag, Zn co-incorporated titania through micro-arc oxidation (MAO) method on metallic Ti substrate. Microstructural characterization reveals that the presence of both Ag NP clusters and micro-sized dicalcium phosphate dehydrate (DCPD) flakes on the surface of Ag, Zn co-incorporated TiO 2 coating. Ag species are mainly present as metallic Ag whereas Zn species tend to exist as Zn2+ within titania. Further, corrosion resistance, antibacterial property and cell biocompatibility of the resultant coatings were assessed. It is revealed that the Ag, Zn co-incorporated TiO 2 coating possesses favourable corrosion resistance, desirable in vitro antibacterial capability and cell biocompatibility without cytotoxicity, which is a promising candidate as a bio-ceramics for Ti-based implant. • Ag, Zn co-incorporated TiO 2 coating has been successfully produced using micro-arc oxidation method with Na 2 Zn-EDTA and Ag nanoparticles as Zn and Ag sources. • During the oxidation, dicalcium phosphate dehydrate flakes of micrometre scales were formed on the surface of Ag, Zn co-incorporated TiO 2 coating. • Ag, Zn co-incorporated TiO 2 coating exhibits excellent antibacterial capability and desirable bone formability. [ABSTRACT FROM AUTHOR]

In the present work, the influence of Ag 2 O content on the microstructural feature, bio-corrosion behaviour and biological property of the resultant Ag-incorporated TiO 2 micro-arc oxidation (MAO) coating is investigated. It is revealed that, with the addition of an increased amount of Ag 2 O nanoparticles (NPs) in the MAO electrolyte, a less defective Ag-incorporated TiO 2 coating with pores of decreased dimensions could be produced, which also exhibits a higher anatase-to-rutile ratio along with a lower Ag 2 O-to-Ag ratio. Further, both antibacterial capability and bone formability of Ag-incorporated TiO 2 coatings were investigated. The results show that the addition of an increased amount of Ag 2 O NPs enhances antibacterial capability of the resultant coating, which also exhibits desirable biocompatibility. This work offers a promising fabrication method for dual functional Ag-incorporated TiO 2 coating with Ag 2 O NPs as Ag source. [ABSTRACT FROM AUTHOR]