Search

Your search keyword '"Li, Jiaxi"' showing total 1 results
Start Over Author "Li, Jiaxi" Topic antioxidants Journal chemical communications
1 results on '"Li, Jiaxi"'

1. Reversible pH-controlled switching of an artificial antioxidant selenoenzyme based on pseudorotaxane formation and dissociation.

Author

Li, Jiaxi, Si, Chengye, Sun, Hongcheng, Zhu, Junyan, Pan, Tiezheng, Liu, Shengda, Dong, Zeyuan, Xu, Jiayun, Luo, Quan, and Liu, Junqiu

Subjects
*ROTAXANES synthesis, *ANTIOXIDANTS, *PH effect, *ORGANOSELENIUM compounds, *GLUTATHIONE peroxidase, *DISSOCIATION (Chemistry), *SYNTHETIC enzymes
Abstract

A pH-responsive artificial selenoenzyme was constructed by reversible binding between organoselenium compound 1 and CB[6] to form a pseudorotaxane-based molecular switch in response to pH stimuli. The glutathione peroxidase (GPx) activity of the artificial selenoenzyme can be switched on/off in a mild and body suitable environment between pH = 7 and pH = 6. [ABSTRACT FROM AUTHOR]

Published
2015
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results