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Your search keyword '"Li, YongXin"' showing total 2 results
Start Over Author "Li, YongXin" Topic proteins Journal chemical communications
2 results on '"Li, YongXin"'

1. Triazine-pyridine chemistry for protein labelling on tyrosine.

Author

Jiang, Hongfei, Zhang, Qing, Zhang, Yue, Feng, Huxin, Jiang, Hao, Pu, Fan, Yu, Rilei, Zhong, Zheng, Wang, Chaoming, Fung, Yi Man Eva, Blasco, Pilar, Li, Yongxin, Jiang, Tao, and Li, Xuechen

Subjects
*TYROSINE, *NITRATION, *PROTEINS, *TRIAZINES, *BIOLOGICAL systems, *CYSTEINE, *CHEMOSELECTIVITY
Abstract

Herein, we discover the new reactivity of the 1,3,5-triazine moiety reacting with a phenol group and report the development of biocompatible and catalyst-free triazine-pyridine chemistry (TPC) for tyrosine labelling under physiological conditions and profiling in the whole proteome. TPC exhibited high tyrosine chemoselectivity in biological systems after cysteine blocking, displayed potential in tyrosine-guided protein labelling, and had bio-compatibility in live cells. [ABSTRACT FROM AUTHOR]

Published
2022
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2. Fluorescence turn-on detection of a protein using cytochrome c as a quencher.

Author

Liao, Dongli, Chen, Jian, Li, Wenying, Zhang, Qingfeng, Wang, Fangyuan, Li, Yongxin, and Yu, Cong

Subjects
*FLUORESCENCE, *PROTEINS, *CYTOCHROME c, *QUENCHING (Chemistry), *APTAMERS
Abstract

A new approach for the sensitive and selective sensing of a protein has been developed. Cytochrome c could quench the fluorescence of a fluorophore labeled aptamer efficiently. The specific binding between the aptamer and the target protein resulted in a turn-on emission signal, which could be used for protein quantification. [ABSTRACT FROM AUTHOR]

Published
2013
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