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By assembling nanotweezers with ATP-splitting aptamers on gold nanorods (AuT123L), we constructed a near-infrared-activated ATP sensing device that could time-controllably image ATP levels in living cells. By replacing the aptamers on the nanotweezers, the nanoplatform can be applied to other important biomolecules, opening up more possibilities for the study of time controllable nanodevices.

Three new ruthenium(ii) complexes containing an N-heterocyclic carbene (NHC) ligand (RuNHC) have been successfully synthesized and proved to be efficient near-infrared (NIR) ECL (electrogenerated chemiluminescence) luminophores. In addition to the advantages of the lower-charge main motif (+1), the much lower oxidation potentials, and the longer metal to ligand charge transfer (MLCT) absorption bands, most importantly, these RuNHC complexes show higher, or at least comparable, ECL efficiency compared with Ru(bpy)32+ under the same experimental conditions; this demonstrates their great potential for applications in the NIR ECL imaging field in the future.

Amperometric monitoring of vesicular dopamine release from live cells using a facilely fabricated gold nanocone electrode.

Hierarchical CoS2 microspheres were prepared and modified with a cationic ionic liquid (IL). The composite shows enhanced oxygen evolution reaction (OER) performances attributed to the fact that the OER equilibrium is driven forward by the IL, according to Le Chatelier's principle, and by the electrostatic affinity generated at the CoS2/electrolyte interface.

A strategy is designed for sensitive detection of tumor biomarker survivin mRNA based on resonance Rayleigh scattering of a single AuNP nanohalo probe that couples large gold nanoparticles (L-AuNPs, 52 nm) with small AuNPs (S-AuNPs, 18 nm) through the affinity interaction between streptavidin and biotin. This core-satellite plasmon ruler is further applied to imaging survivin mRNA in living cells.

Using single stranded DNA (ssDNA) as a distance controller and Au nanoparticles (NPs) functionalized with ssDNA as novel energy-transfer nanoprobes, an ultrasensitive energy-transfer based photoelectrochemical protein biosensor was realized.

A mesoporous silica film-assisted amplification method is reported for the first time for the sensitive electrochemiluminescence detection of cancer cells.

A dual target-recycling amplification strategy for sensitive detection of microRNAs based on duplex-specific nuclease and catalytic hairpin assembly was reported for the first time.

The reaction between MO and NaBH4 catalyzed by Ag NPs has been studied. Ag NPs catalyzed the reduction of MO rapidly, while adding CTAB into the solution caused the regeneration of MO. Thus, reversible catalysis for the reaction between MO and NaBH4 by Ag NPs was discovered for the first time.

An ideal nanoporous poly(N-isopropylacrylamide) membrane has been fabricated in glass microchannels by means of spatially controlled photopatterning technology for a high level of enrichment and cleanup of nucleic acids.

Based on the K-doped graphene-CdS:Eu NC composites and the nicking endonuclease (NEase) assisted strand-scission cycle, we have developed an ultrasensitive and selective electrochemiluminescence (ECL) DNA biosensor using the G-quadruplex-hemin-based DNAzyme which acts as an electrocatalyst for the reduction of H(2)O(2), the coreactant of CdS:Eu NCs ECL.

A new dual-functional electrochemical biosensor for the detection of prostate specific antigen (PSA) and telomerase activity was successfully developed based on a sandwich immunobinding format and telomerization assisted hemin-G-quadruplex-based DNAzyme as a biolabel.

Continuous CaCO(3) hollow nanoparticle generation at room temperature with simultaneous molecule doping is realized on a liquid-gas dual phase microfluidic system.

This work is the first report on the energy transfer between CdS quantum dots and Au nanoparticles for photoelectrochemical biosensing applications.

Efficient electrochemiluminescence (ECL) quenching was achieved by functionalized CdTe quantum dots (QDs) through ECL energy scavenging, based on which ultrasensitive antigen detection could be realized.

The quenching of electrochemiluminescence (ECL) from a CdS:Mn nanocrystal film by proximal Au nanoparticles was observed as a result of Förster energy transfer, while an enhancement of ECL takes place after hybridization with target DNA due to the energy transfer of ECL excited surface plasmon resonances in AuNPs to the CdS:Mn NCs at large separation, based on which an ultrasensitive and specific DNA biosensor was constructed.

CdS nanoparticles composited with carbon nanotubes not only enhances their electrochemiluminescent intensity but also decreases their ECL starting potential; such a property would promote the application of quantum dots in fabricating sensors for chemical and biochemical analysis.

A sensitive enzyme-based FET biosensor for lactate has been obtained by introducing MnO2 nanoparticles at the gate surface via a layer-by-layer assembling method.