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Your search keyword '"Li, Jiaxi"' showing total 2 results
Start Over Author "Li, Jiaxi" Journal chemical communications
2 results on '"Li, Jiaxi"'

1. An ion signal responsive dynamic protein nano-spring constructed by high ordered host–guest recognition.

Author

Si, Chengye, Li, Jiaxi, Luo, Quan, Hou, Chunxi, Pan, Tiezheng, Li, Hongbin, and Liu, Junqiu

Subjects
*HOST-guest chemistry, *TRIPEPTIDES, *CHIMERIC proteins, *PROTEIN research, *NANOSTRUCTURES
Abstract

A protein self-assembly nano-spring was developed through host–guest interactions between cucurbit[8]uril and tripeptide FGG tags of fusion protein FGG-recoverin-GST. Fine control of the conformational changes of the Ca2+-responsive domain allows for a 50% stretch of the protein nano-spring as it switches from the contracted state to the extended state. [ABSTRACT FROM AUTHOR]

Published
2016
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2. Reversible pH-controlled switching of an artificial antioxidant selenoenzyme based on pseudorotaxane formation and dissociation.

Author

Li, Jiaxi, Si, Chengye, Sun, Hongcheng, Zhu, Junyan, Pan, Tiezheng, Liu, Shengda, Dong, Zeyuan, Xu, Jiayun, Luo, Quan, and Liu, Junqiu

Subjects
*ROTAXANES synthesis, *ANTIOXIDANTS, *PH effect, *ORGANOSELENIUM compounds, *GLUTATHIONE peroxidase, *DISSOCIATION (Chemistry), *SYNTHETIC enzymes
Abstract

A pH-responsive artificial selenoenzyme was constructed by reversible binding between organoselenium compound 1 and CB[6] to form a pseudorotaxane-based molecular switch in response to pH stimuli. The glutathione peroxidase (GPx) activity of the artificial selenoenzyme can be switched on/off in a mild and body suitable environment between pH = 7 and pH = 6. [ABSTRACT FROM AUTHOR]

Published
2015
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