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Start Over Author "Preslar, Adam T." Journal chemical communications
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2. Esterase-activated release of naproxen from supramolecular nanofibres.

Author

Conda-Sheridan, Martin, Stupp, Samuel I., Lee, Sungsoo S., and Preslar, Adam T.

Subjects
ESTERASES, NAPROXEN, SUPRAMOLECULAR chemistry, AMPHIPHILES, PEPTIDES, NANOSTRUCTURES
Abstract

Nanofibre forming peptide amphiphiles were conjugated to naproxen through an esterase-sensitive linker. The amount of naproxen released, in the presence of enzymes, was influenced by the linker conjugating the drug to the supramolecular assembly. In vitro studies showed the anti-inflammatory activity of the released drug was maintained. [ABSTRACT FROM AUTHOR]

Published
2014
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