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Start Over Author "Seo Won Cho" Journal chemical communications
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1. A systematic study on the discrepancy of fluorescence properties between in solutions and in cells: super-bright, environment-insensitive benzocoumarin dyes

Author

Sourav Sarkar, Seo Won Cho, Yun Lim Jung, Hajung Roh, Jinseong Jeon, Ye Jin Reo, Jinmyoung Joo, S.H. Kim, Yun Jae Yang, Hye-Rim Kim, Yong Woong Jun, Kyo Han Ahn, Mingchong Dai, Yusung Jin, Subhankar Singha, and Changill Ban

Subjects
Aqueous medium, Chemistry, Metals and Alloys, General Chemistry, Photochemistry, Fluorescence, Catalysis, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Solutions, Coumarins, Cell Line, Tumor, Materials Chemistry, Ceramics and Composites, Humans, Fluorescent Dyes
Abstract

The benzocoumarin dyes fluoresce negligibly in aqueous media but very strongly in cells, whereas representative conventional dyes display contrasting behaviour; the distinct emission behaviour of the fluorophores in organic solutions, in aqueous media, and in cell convinces the uniqueness of the cellular environment. The in cellulo superbright benzocoumarins also reveal an environment-insensitive emission behaviour, which is required for the reliable analysis via ratiometric imaging.

Published
2020

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