1. Microtubes self-assembled from a cholesterol-modified nucleoside
- Author
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Norbert Bannert, Paula Pescador, Andreas Herrmann, Nicolai Brodersen, Daniel Huster, Holger A. Scheidt, Jürgen Liebscher, Anna Arbuzova, Gudrun Holland, and Martin Loew
- Subjects
Outer diameter ,Molecular Structure ,Cholesterol ,Metals and Alloys ,Nucleosides ,General Chemistry ,Modified nucleosides ,Catalysis ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Self assembled ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,Microscopy, Electron, Transmission ,Materials Chemistry ,Ceramics and Composites ,Microscopy, Electron, Scanning ,Molecule ,Organic chemistry ,lipids (amino acids, peptides, and proteins) ,Nucleoside ,Phospholipids - Abstract
We describe the formation of lipid microtubes from a novel cholesterol-modified nucleoside in binary mixture with phospholipids. Stable cylindrical structures with an outer diameter of 2-3 microm and a length of 20-40 microm were formed. By varying the preparation conditions, thinner tubules with nanometre-scale diameters could also be obtained.
- Published
- 2010