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Your search keyword '"Hypnotics and Sedatives isolation & purification"' showing total 4 results
Start Over Descriptor "Hypnotics and Sedatives isolation & purification" Journal chemical pharmaceutical bulletin
4 results on '"Hypnotics and Sedatives isolation & purification"'

1. Pharmacologically active components from a Peruvian medicinal plant, huira-huira (Culcitium canescens H. & B.).

Author

Okuyama E, Umeyama K, Ohmori S, Yamazaki M, and Satake M

Subjects
Analgesics pharmacology, Analgesics, Non-Narcotic isolation & purification, Analgesics, Non-Narcotic pharmacology, Animals, Hypnotics and Sedatives pharmacology, Male, Mice, Microsomes, Liver drug effects, Microsomes, Liver metabolism, Naphthalenes pharmacology, Plant Extracts isolation & purification, Plant Extracts pharmacology, Plants, Medicinal, Structure-Activity Relationship, Analgesics isolation & purification, Hypnotics and Sedatives isolation & purification, Naphthalenes isolation & purification
Abstract

The methanol extract of Huira-Huira (Culcitium canescens) showed analgesic effects in acetic acid-induced writhing and tail pressure tests, and it also produced potent prolongation of hypnosis induced by pentobarbital. The latter activity was used as an isolation-guide to determine the active components which were identified as dehydrocacalohastine, cacalohastine and cacalonol.

Published
1994
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2. Ascaridole as a pharmacologically active principle of "Paico," a medicinal Peruvian plant.

Author

Okuyama E, Umeyama K, Saito Y, Yamazaki M, and Satake M

Subjects
Analgesics pharmacology, Animals, Anthelmintics pharmacology, Cyclohexane Monoterpenes, Hypnotics and Sedatives pharmacology, Male, Mice, Mice, Inbred Strains, Peru, Terpenes pharmacology, Analgesics isolation & purification, Anthelmintics isolation & purification, Hypnotics and Sedatives isolation & purification, Monoterpenes, Peroxides, Plants, Medicinal chemistry, Terpenes isolation & purification
Abstract

"Paico," Chenopodium ambrosioides L., is a traditional Peruvian medicine which is considered to be nervine, antirheumatic, anthelmintic, etc. An attempt was made to isolate the component having sedative and/or analgesic properties from "Paico" and "Aritasou" (the Japanese name for C. ambrosioides). Ascaridole was identified as the active principle in both materials.

Published
1993
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4. Isolation of sedative principles from Perilla frutescens.

Author

Honda G, Koezuka Y, Kamisako W, and Tabata M

Subjects
Animals, Hexobarbital pharmacology, Hypnotics and Sedatives pharmacology, Male, Mice, Sleep drug effects, Sterols pharmacology, Hypnotics and Sedatives isolation & purification, Plants, Medicinal analysis
Published
1986
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