23 results on '"Spring, David R."'
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2. A cell-active cyclic peptide targeting the Nrf2/Keap1 protein–protein interaction.
3. A cell-active peptide targeting the Nrf2/Keap1 protein-protein interaction
4. All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading
5. Rapid and robust cysteine bioconjugation with vinylheteroarenes
6. Demonstration of the utility of DOS-derived fragment libraries for rapid hit derivatisation in a multidirectional fashion
7. Sulfatase-cleavable linkers for antibody-drug conjugates
8. Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody–drug conjugates
9. Diversity-oriented synthesis of heterocycles and macrocycles by controlled reactions of oxetanes with α-iminocarbenes† †Electronic supplementary information (ESI) available: Synthetic protocols, 1H/13C NMR and HR mass spectra are provided. CCDC 1443618–1443620 and 1534812–1534815. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c7sc00964j Click here for additional data file. Click here for additional data file
10. Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst† †Dedicated to Professor Stuart L. Schreiber on the occasion of his 60th birthday. ‡ ‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c6sc05313k Click here for additional data file
11. A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody–drug conjugates
12. Efficient development of stable and highly functionalised peptides targeting the CK2α/CK2β protein–protein interaction
13. Synthesis of a novel polycyclic ring scaffold with antimitotic properties via a selective domino Heck–Suzuki reaction† †Electronic supplementary information (ESI) available: Full experimental details, 1H and 13C NMR spectra and X-ray crystallographic data for compound 4d. CCDC 936207. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c4sc02547d Click here for additional data file. Click here for additional data file
14. Stapled peptides as a new technology to investigate protein–protein interactions in human platelets
15. Second-generation CK2α inhibitors targeting the αD pocket
16. Specific inhibition of CK2α from an anchor outside the active site
17. A new Pseudomonas quinolone signal (PQS) binding partner: MexG
18. Synthesis of a novel polycyclic ring scaffold with antimitotic properties via a selective domino Heck–Suzuki reaction
19. Functionalised staple linkages for modulating the cellular activity of stapled peptides.
20. All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading
21. Diversity-oriented synthesis of heterocycles and macrocycles by controlled reactions of oxetanes with α-iminocarbenes
22. Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.
23. A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.
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