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3 results on '"Adam J. Rosenberg"'

1. ChemInform Abstract: Copper- and Palladium-Catalyzed Amidation Reactions for the Synthesis of Substituted Imidazo[4,5-c]pyridines

Author

Robert Wilson, Lauren Kaminsky, Adam J. Rosenberg, and Daniel A. Clark

Subjects
Chemistry, chemistry.chemical_element, General Medicine, Condensation reaction, Combinatorial chemistry, Copper, Palladium, Catalysis
Abstract

Imidazo[4,5-c]pyridines were synthesized in three steps utilizing a palladium-catalyzed amidation/cyclization strategy. N-Aryl substrates were synthesized using copper-catalyzed amidation of 3-amino-N-Boc-4-chloropyridine. Complementary protocols for the selective chlorination of imidazo[4,5-c]pyridines at the C2 and C7 positions were also developed.

Published
2014
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2. ChemInform Abstract: Synthesis of 2-Amino-imidazo[4,5-b]pyridines

Author

Adam J. Rosenberg, Daniel A. Clark, Abraham J. Jordan, and Theresa M. Williams

Subjects
Simple (abstract algebra), Chemistry, Rapid access, Regioselectivity, General Medicine, Combinatorial chemistry
Abstract

The presented approach is completely regioselective, procedurally simple, and provides rapid access to previously difficult to access moieties.

Published
2013
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3. ChemInform Abstract: Synthesis of Imidazo[4,5-b]pyridines and Imidazo[4,5-b]pyrazines by Palladium- Catalyzed Amidation of 2-Chloro-3-aminoheterocycles

Author

Jinbo Zhao, Daniel A. Clark, and Adam J. Rosenberg

Subjects
chemistry, Organic chemistry, chemistry.chemical_element, General Medicine, Catalysis, Palladium
Abstract

The process allows a quick access to various natural products and biologically interesting title compounds with substituents at N-1 and C-2.

Published
2012
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