Search

A new approach for selective modification of cysteine-containing peptides through gold-mediated oxidative allene–thiol coupling reaction in aqueous medium is developed.

Title reaction proceeds smoothly in aqueous solution under mild reaction conditions to give a wide variety of aromatic and aliphatic amides (III).

A series of non-coplanar and flexible xanthone derivatives (III), (IV) and (VI) is synthesized as potential α-glucosidase inhibitors.