Author: "Pierre Dextraze" / Journal: cheminform - Searchworks@Jio Institute Digital Library Search Results

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Start Over Author "Pierre Dextraze" Journal cheminform

Author: E. Bernstein, D. P. Taylor, J. S. New, W. G. Lobeck, Pierre Dextraze, Michael S. Eison, D. L. Jun. Temple, J. P. Yevich, and Frank D. Yocca
Subjects: Stereochemistry, medicine.drug_class, Chemistry, medicine, Atypical antipsychotic, General Medicine
Published: 2010
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Author: D. P. Taylor, Sandra L. Moon, Pierre Dextraze, and Joseph P Yevich
Subjects: Piperazine, chemistry.chemical_compound, chemistry, In vivo, Stereochemistry, General Medicine, Serotonin, Receptor
Abstract: A number of N-substituted 1-(5-fluoro-2-pyrimidinyl)piperazine derivatives were prepared and evaluated for binding to sigma and serotonin 5-HT 1A and 5-HT 2 receptor subtypes as well as for their protection against nitrogen anoxia-induced lethality in rats. Although various compounds exhibited good binding affinity and/or anti-anoxic effects, there was no obvious correlation between their receptor binding and in vivo effects.
Published: 2010
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Author: John F. Kadow, Thomas Alstadt, Shu-Hui Chen, Pierre Dextraze, Karen Du, Craig Fairchild, Jerzy Golik, Steven Hansel, Kathy A. Johnston, Robert A. Kramer, and et al. et al.
Subjects: Chemistry, Structure–activity relationship, Nanotechnology, General Medicine, Combinatorial chemistry
Published: 2010
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