Search

Your search keyword '"Santhakumar A"' showing total 26 results
Start Over Author "Santhakumar A" Journal cheminform
26 results on '"Santhakumar A"'

1. ChemInform Abstract: Rapid Access to Pyrido[1,2,5]triazepin-4-ones Through Intramolecular Nucleophilic Aromatic Substitution

Author

Sandra I. Baltatu, Shujuan Jin, Tomaszewski Miroslaw, Vijayaratnam Santhakumar, and Olivier St-Jean

Subjects
Substitution reaction, chemistry.chemical_compound, Radical-nucleophilic aromatic substitution, chemistry, Nucleophilic aromatic substitution, Stereochemistry, Intramolecular force, Yield (chemistry), Hydrazine, Rapid access, General Medicine, Medicinal chemistry
Abstract

The condensation of ketoamides (I) and (IV) with methyl hydrazine produces hydrazones which undergo intramolecular nucleophilic aromatic substitution to yield the title compounds (III) and their benzo analogues (V).

Published
2012

8. ChemInform Abstract: An Efficient New Protocol for the Formation of Unsymmetrical Tri- and Tetrasubstituted Ureas

Author

Robert A. Batey, Vijayaratnam Santhakumar, Scott D. Taylor, and Chiaki Yoshina-Ishii

Subjects
genetic structures, Chemistry, Amine gas treating, General Medicine, Alkylation, Combinatorial chemistry
Abstract

A new method for producing unsymmetrical, tetrasubstituted ureas from N, N′-carbonyldiimidazole (CDI) is presented. Carbamoyl imidazolium salts are prepared from the reaction of CDI with a secondary amine, followed by alkylation with MeI. Secondary amines add with ease to imidazolium salts at room temperature to give unsymmetrical, tetrasubstituted ureas in excellent yields.

Published
2010

9. ChemInform Abstract: A New Protocol for the Formation of Carbamates and Thiocarbamates Using Carbamoyl Imidazolium Salts

Author

Scott D. Taylor, Robert A. Batey, Vijayaratnam Santhakumar, and Chiaki Yoshina-Ishii

Subjects
chemistry.chemical_compound, chemistry, Reagent, Organic chemistry, General Medicine, Phenols, Thiocarbamates
Abstract

Carbamoyl imidazolium salts are demonstrated to act as useful carbamoylation reagents, in reactions with alcohols, phenols, thiols and thiophenols to form carbamates and thiocarbamates under relatively mild conditions. The salts are stable and easily prepared from the corresponding amines using CDI.

Published
2010

11. ChemInform Abstract: Aminolysis of 3-Phenyl Propylthiol Esters Leading to Diverse Sets of Amides

Author

Tomaszewski Miroslaw, Vijayaratnam Santhakumar, and Pandiaraju Subramanian

Subjects
Silver salts, Reaction conditions, Aminolysis, Chemistry, Reagent, fungi, food and beverages, General Medicine, Combinatorial chemistry, Linker, Solution phase
Abstract

3-Phenyl propylthiol esters were investigated as “activatable” solution phase linkers. These linkers can be activated with silver salts and upon treatment with amines can be converted to the corresponding amides. Under unactivated conditions, the linker is stable to a variety of reagents and reaction conditions including treatment with amines.

Published
2009

Catalog

Books, media, physical & digital resources
See catalog results