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Your search keyword '"ROBERT MACRAE"' showing total 4 results
Start Over Author "ROBERT MACRAE" Journal chemischer informationsdienst
4 results on '"ROBERT MACRAE"'

1. ChemInform Abstract: EXTENSION OF THE ′HANDLE′ METHOD OF PEPTIDE SYNTHESIS, THE USE OF 4-PICOLYLOXYCARBONYLHYDRAZIDES

Author

Robert Macrae and Geoffrey T. Young

Subjects
Coupling, chemistry.chemical_compound, Fragment (logic), Chemistry, Hydrogenolysis, Product (mathematics), Peptide synthesis, General Medicine, Extension (predicate logic), Hydrazide, Combinatorial chemistry
Abstract

The 4-picolyloxycarbonylhydrazide of a carboxy-terminal amino-acid [e.g.(I)] provides a weakly basic ‘handle’ by which the coupling product can readily be isolated at each stage of peptide synthesis; then hydrogenolysis of the 4-picolyl group yields the hydrazide required for fragment coupling.

Published
1974
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