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Your search keyword '"lavendamycin"' showing total 3 results
Start Over Descriptor "lavendamycin" Journal chemischer informationsdienst
3 results on '"lavendamycin"'

1. ChemInform Abstract: Synthetic Approach to the Antitumor Antibiotic Lavendamycin: A Synthesis of De-methyllavendamycin Methyl Ester

Author

Miko Okazaki, Satoshi Hibino, K. Sato, Masataka Ichikawa, and Itsuko Morita

Subjects
chemistry.chemical_compound, chemistry, Bicyclic molecule, Stereochemistry, medicine.drug_class, Antibiotics, medicine, Organic chemistry, General Medicine, Phenols, Lavendamycin, Quinone
Abstract

Synthese a partir de l'ester de methyle du tryptophane et de benzyloxy-8 quinoleinecarbaldehyde-2 via l'oxydation du [dibromo-5,7 hydroxy-8 quinolyl-2]-1 β-carbolinecarboxylate-3 de methyle

Published
1984
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3. ChemInform Abstract: FORMAL SYNTHESIS OF LAVENDAMYCIN METHYL ESTER: THE REGIOSELECTIVE SYNTHESIS TO THE BROMOQUINOLINEQUINONE SYSTEMS OF KEY INTERMEDIATE

Author

Takashi Ishizu, Satoshi Hibino, Masataka Ichikawa, Miko Okazaki, and K. Sato

Subjects
chemistry.chemical_classification, chemistry.chemical_compound, Formal synthesis, Pictet–Spengler reaction, chemistry, Bicyclic molecule, Stereochemistry, Regioselectivity, General Medicine, Lavendamycin, Aldehyde
Abstract

Synthese de l'[hydroxy-8 quinolyl-2]-1 methyl-4 β-carbolinecarboxylate-3 d'ethyle (A) par reaction de Pictet Spengler de benzyloxy-8 quinoleinecarbaldehyde-2 et de β-methyl tryptophanate d'ethyle suivie d'hydrogenolyse; a partir de A par l'intermediaire de bromation puis d'oxydation, obtention des esters d'ethyle et de methyle de l'acide [bromo-7 dihydro-5,8 dioxo-5,8 quinolyl-2]-1 methyl-4 β-carbolinecarboxylique-3; l'ester de methyle a deja ete transforme en ester de methyle de lavendamycine

Published
1985
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