1. Antagonists of protein–protein interactions
- Author
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Andrea G. Cochran
- Subjects
Models, Molecular ,Phage display ,Molecular Sequence Data ,Clinical Biochemistry ,Chemical biology ,Peptide ,Computational biology ,Biology ,Pharmacology ,Binding, Competitive ,Biochemistry ,Protein–protein interaction ,Disease therapy ,Peptide Library ,Drug Discovery ,Amino Acid Sequence ,Molecular Biology ,chemistry.chemical_classification ,Binding Sites ,Drug discovery ,General Medicine ,chemistry ,Structural biology ,Drug Design ,Molecular Medicine ,Dimerization ,Protein Binding - Abstract
Protein–protein interactions are often attractive, but not straightforward, targets for disease therapy. Two strategies for identifying inhibitors of these interactions, peptide phage display and high-throughput screening, have recently shown new promise.
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