1. SYNTHESIS OF NEOBAVAISOFLAVONE
- Author
-
Toshihide Yamada, Shûichi Hayashi, Mitsuo Masumura, Mitsuru Nakayama, Masao Tsukayama, and Tokunaru Horie
- Subjects
Hydrolysis ,chemistry.chemical_compound ,Chemistry ,Hydrogenolysis ,Formic acid ,Daidzein ,Condensation ,Neobavaisoflavone ,Organic chemistry ,General Chemistry ,Alkali metal ,Chroman derivative - Abstract
Condensation of 7-benzoyldaidzein (III) with 2-methyl-3-buten-2-ol gave 7-benzoyl-3′-(3-methyl-2-butenyl)daidzein (IV). Hydrolysis of IV with dilute alkali gave 3′-(3-methyl-2-butenyl)daidzein (neobavaisoflavone) (I), which was converted into isoneobavaisoflavone (VI) when heated with formic acid. 7-Benzyldaidzein (VII) was condensed with 2-methyl-3-buten-2-ol to give a chroman derivative (VIII), which was converted into VI by hydrogenolysis.
- Published
- 1975
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