1. Bioactive Alkaloids of Stephania sinica Showing Anti-Drug-Resistance Activity.
- Author
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Wang, Xinzhu, Qi, Jun, Zhao, Peipei, Liu, Chao, Yang, Meng, Wang, Hong, Hu, Yingying, Liao, Zhixin, and Xia, Xuekui
- Subjects
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ALKALOIDS , *LIFE sciences , *ISOQUINOLINE alkaloids - Abstract
I Stephania sinica i Diels, a slightly fleshy deciduous vine in the I Stephania i species, belongs to the family Menispermaceae [[1]] and is widely distributed in the southwest of China, such as Sichuan, Yunnan, and Guangxi Province. The cytotoxic and apoptosis activity of compound B 1 b was also tested, which showed moderate activity against MGC-803, NCI-H460, SKOV3, and T24 (hydroxycamptothecin was the positive control) (Table 2). All isolated compounds ( B 1-6 b ) were screened for their antibacterial activity and antibiotic resistance activity towards a panel of bacteria. [Extracted from the article]
- Published
- 2020
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