1. A New Isochroman Derivative from the Endophytic Microsphaeropsis arundinis.
- Author
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Qin, Shao-Huan, Zhao, Li-Xing, Yang, Ya-Bin, Hu, Ming, and Ding, Zhong-Tao
- Subjects
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COELOMYCETES , *ORGANIC oxides , *ANTIBACTERIAL agents , *OXIDANT status , *PATHOGENIC fungi , *ENDOPHYTES - Abstract
A new isochroman derivative, erythro-2-methyl-5-hydroxyphenylpropane-7,8-diol ( 1), and three known compounds including of (4S)-4,8-dihydroxy-3,4-dihydro-1(2H)-naphthalen-1-one ( 2), (4S)-4,6,8-trihydroxy-3,4-dihydro-1(2H)-naphthalen-1-one ( 3), and chrysogeside D ( 4), were isolated from Microsphaeropsis arundinis. Compounds 3 and 4 were first found in Microsphaeropsis. The antibacterial, antiphytopathogenic, and antioxidant activities of these compounds were evaluated. Compounds 1 and 4 inhibited Alternaria tenuissima, a pathogenic fungus causing root rot of Panax notoginseng with MICs at 64 μg/mL, which showed the ecological function of the endophyte for its host plant. [ABSTRACT FROM AUTHOR]
- Published
- 2017
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