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Abstract: The manuscript describes a straightforward and atom‐efficient method for the synthesis of α‐alkylidene‐β‐lactams using sorbyl tosylate and imines/1‐azadienes at high temperature (80 °C). The Density functional theory calculations have shown the prevalence of the first order kinetics in these [2+2] cycloadditions to produce mixture of 3‐butadienyl‐azetidin‐2ones and 3‐but‐2‐enylidene‐azetidin‐2‐ones in good yields. The 3‐but‐2‐enylidene‐azetidin‐2‐ones have also shown antimicrobial activity against the E. coli, S. aureus, P. aeruginosa, B. cereus and B. subtilis. [ABSTRACT FROM AUTHOR]

Abstract: Here in, novel excited state intramolecular charge transfer (ESIPT)‐modulated fluorophore based on diphenylpyrimidinone DPHQ has been designed and synthesized. DPHQ shows selective 8‐fold ‘turn‐on’ fluorescence response with Cd2+/Zn2+ in buffer (containing 1% CH3CN, pH 7.2) with low detection limits of 55.7/2.7 nM accompanied with a fluorescent colour change from colourless to cyan. DPHQ–Cd2+ ensemble undergo selective fluorescence quenching with nucleoside triphosphates but it is silent to nucleoside di‐and mono‐phosphates. It can detect 58.4 nM concentration of adenosine triphosphate (ATP). The binding mode and sensing mechanism of DPHQ with Cd2+/Zn2+ was supported by the change in optical behaviors, density functional theory (DFT) calculations and Job's plot. DPHQ was successfully used for construction of ‘Set‐Reset’ memorized logic devices and OR, INHIBIT logic gates. As practical applications of DPHQ, we utilized DPHQ for detection of Cd2+/Zn2+ in blood serum and quantification of Zn2+ in tap water samples. [ABSTRACT FROM AUTHOR]

Abstract: A novel, efficient and one‐pot multicomponent copper‐catalyzed amination of N‐pyridyl imines is described. This, one‐pot, multicomponent reaction, in which imine acts as a directing group by chelating to the metal core, affords a domino approach for the transformation of the commercial pyridinamines, aldehydes and azide into valuable imidazo[4, 5‐b]pyridines with wide substrate extent and diversity. [ABSTRACT FROM AUTHOR]