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NiCo (Nickel-cobalt) nanoparticles were obtained by the chemical reduction method on functionalized multi-walled carbon nanotubes. After this process, chronoamperometry, cyclic voltammetry, and amperometric methods were used to investigate the electrochemical and electrocatalytic behavior of NiCo@f-MWCNT against glucose oxidation. In addition, the NiCo@f-MWCNT nanocomposites were analyzed by characterization techniques such as X-Ray Diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Transmission Electron Microscopy (TEM), and Atomic Force Microscopy (AFM) in terms of the morphological and atomic structure of prepared nanomaterials. The sensitivity and limit of detection the non-enzymatic glucose sensor (NiCo@f-MWCNT) were calculated as 10,015 μA/mM−1 cm−2 0.26 μM, respectively. As a result of these studies and experiments, the NiCo@f-MWCNT nanocomposite is a really good sensor and their stability showed that the current nanomaterials expressed to be new material for the electrochemical detection of glucose.

In this study, a glucose sensor modified with activated carbon supported gold-nickel (AuNi@AC) metal nanoparticles was prepared for the early diagnosis of diabetes. Electrochemical tests were carried out by determining the optimum working conditions of the prepared glucose sensor. The characterization analyses of the designed glucose sensor were performed by Transmission Electron Microscopy (TEM), X-Ray Diffraction (XRD), X-Ray Photoelectron Spectroscopy (XPS) and Raman Spectroscopy. It was determined that the average particle size of the nanoparticles in the AuNi alloy structure was 2.03 ± 0.37 nm. The determined detection limit of the AuNi@AC nanosensor was calculated as 0.41 μM as a result of the high linear range provided up to 1.7 mM. In addition, the sensitivity of AuNi@AC nanosensor to glucose, which has a high sensitivity value of 1955 μA mM−1 cm−2, was determined.

In this study, Antimicrobial, Antifungal and Antibiofilm activity tests on 16 bacteria and 2 fungi of Salvia marashica Ilcim, Celep & Dogan and Salvia caespitosa Montbret & Aucher ex Benth species were performed by Agar Well Diffusion and Microdilution methods. Salvia species showed sensitivity with a zone diameter of 12–16 mm. Concentrations of 0.5 mg/ml to 16 mg/ml by the dilution method were used to determine the Minimum inhibited concentration (MIC) and Minimum bactericidal concentration (MBK). The MIC values of the plants are mostly 0.5 mg/ml - 4 mg/ml and MBC values are between 0.5 mg/ml - 8 mg/ml. Antifungal activity findings are remarkable on the species and it has been observed to have very high effects especially on Candida parapsilosis. When the antioxidant research findings are examined; It was observed that Salvia marashica and Salvia caespitosa plants have approximately 75% antioxidant activity at 1 mg/ml, and findings mostly directly proportional between concentrations and antioxidant activity capacity were recorded. MCF-7 and HUVEC cell lines were used to investigate anticancer activity properties. In line with the findings, while the IC50 value of Salvia marashica on the MCF-7 Cell line was 0.125 mg/ml, it was 1.65 mg/ml in the HUVEC cell line, while the IC50 value of Salvia caespitosa on the MCF-7 Cell line was 0.115 mg/ml in the HUVEC Cell line. It was found to be 9.87 mg/ml. It has been proven that both Salvia species have a cytotoxic effect on the MCF-7 Cell line.