Search

The article in ChemPlusChem discusses the use of Raman optical activity spectra to monitor the conformation and protonation states of glutathione. By combining this technique with density functional theory and molecular dynamics computations, researchers can deduce potential energy maps from the spectra. These maps can be used to verify or improve common force fields. The study found that the pH had a limited effect on the backbone conformation of glutathione. The full details of the research can be found in the article by Petr Bouř and his colleagues. [Extracted from the article]