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The article evaluates the role of exhaled nitric oxide (NO) for the investigation of chronic cough, especially of nonasthmatic eosinophilic bronchitis (NAEB). The results indicate that exhaled NO measurement may be useful as part of the initial evaluation for chronic cough, especially for the exclusion of NAEB. A low level of NO suggested little likelihood of NAEB for the nonasthamtic patients with chronic cough.

The article presents evidence for the diagnosis and treatment of cough due to chronic bronchitis. Chronic bronchitis is a bronchi disease where there is occurrence of cough and sputum expectoration when other respiratory or cardiac causes for the chronic productive cough are not considered. It is a cough phlegm syndrome and is caused by the interplay of noxious inhaled agents host factors. This interaction results in chronic inflammation in the walls and lumen of the airways. Researchers have found that avoidance is the most effective way to reduce or eliminate cough in patients with chronic bronchitis.

This article focuses on a study related to the assessment of citric acid cough threshold (CACT) in patients with chronic cough due to gastroesophageal reflux disease (GERD) before and 3 months after laparoscopic Toupet fundoplication. GERD is among the most common causes of chronic cough in all age groups, exceeded in frequency only by postnasal drip syndrome and asthma. Moreover, chronic cough can be the sole presenting manifestation of GERD. However, up to 75% patients with GERD-induced cough may have no GI symptoms. In this preliminary study in a group of GERD patients with chronic cough before antireflux surgery, the researchers observed the relationship between subjective and objective evaluations of cough and means of CACT values.