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2. Phase 3 Study of Reslizumab in Patients With Poorly Controlled Asthma Effects Across a Broad Range of Eosinophil Counts

Author

Corren, Jonathan, Weinstein, Steven, Janka, Lindsay, Zangrilli, James, and Garin, Margaret

Subjects
phase 3, eosinophil, respiratory system, asthma, reslizumab
Abstract

BackgroundIL-5, a mediator of eosinophil activity, is an important potential treatment target in patients with uncontrolled asthma. The efficacy of reslizumab, a humanized anti-human IL-5 monoclonal antibody, has been characterized in patients with blood eosinophils ≥ 400 cells/μL. This study further characterizes the efficacy and safety of reslizumab in patients with poorly-controlled asthma, particularly those with eosinophils

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