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16 results on '"MacNee, William."'

3. Hospitalized Exacerbations of COPD: Risk Factors and Outcomes in the ECLIPSE Cohort

Author

Müllerova, Hana, Maselli, Diego J., Locantore, Nicholas, Vestbo, Jørgen, Hurst, John R., Wedzicha, Jadwiga A., Bakke, Per, Agusti, Alvar, Anzueto, Antonio, Ivanov, Yavor, Kostov, Kosta, Bourbeau, Jean, Fitzgerald, Mark, Hernández, Paul, Killian, Kieran, Levy, Robert, Maltais, Francois, O´Donnell, Denis, Krepelka, Jan, Vestbo, Jørgen, Wouters, Emiel F. M., Quinn, Dean, Bakke, Per, Kosnik, Mitja, Agusti, Alvar, Feschenko, Yuri, Gavrisyuk, Volodymyr, Yashina, Lyudmila, MacNee, William, Singh, S. David, Wedzicha, Jadwiga, Anzueto, Antonio, Braman, Sidney, Casaburi, Richard, Celli, Bart, Giessel, Glenn, Gotfried, Mark, Greenwald, Gary, Hanania, Nicola, Mahler, Don, Make, Barry, Rennard, Stephen, Rochester, Carolyn, Scanlon, Paul, Schuller, Dan, Sciurba, Frank, Sharafkhaneh, Amir, Siler, Thomas, Silverman, Edwin, Wanner, Adam, Wise, Robert, Zu Wallack, Richard, Bakke, Per, Coxson, Harvey, Edwards, Lisa, Lomas, David, MacNee, William, Silverman, Edwin, Tal-Singer, Ruth, Vestbo, Jørgen, Yates, Julie, Agusti, Alvar, Calverley, Peter, Celli, Bartolome, Crim, Courtney, Miller, Bruce, MacNee, William, Rennard, Stephen, Tal-Singer, Ruth, and Wouters, Emiel

Published
2015
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9. The effects of cigarette smoking on pulmonary hemodynamics

Author

Skwarski, Kristopher M., Gorecka, Dorota, Sliwinski, Pawel, Hogg, James C., and MacNee, William

Subjects
Lungs -- Blood-vessels, Lung diseases, Obstructive -- Physiological aspects, Smoking -- Physiological aspects, Pulmonary circulation -- Physiological aspects, Health, Physiological aspects
Abstract

Neutrophils are delayed in transit in the pulmonary circulation during smoking which could reflect smoke-induced changes in local hemodynamics. The purpose of this study was to measure the changes in [...]

Published
1993

10. Environmental Mechanisms

Author

MacNee, William and Donaldson, Kenneth

Subjects
Lung diseases, Obstructive -- Causes of -- Health aspects, Air pollution -- Health aspects, Health, Causes of, Health aspects
Abstract

Air pollution as a trigger for exacerbations of COPD has been recognized for [is greater than] 50 years, and has led to the development of air quality standards in many [...]

Published
2000

13. Pulmonary Hypertension and Right Ventricular Function in Patients with COPD

Author

Biernacki, Wojciech, Flenley, David C., Muir, Alexander L., and MacNee, William

Abstract

In 100 patients with chronic obstructive pulmonary disease (COPD), we found no significant correlation between simultaneous measurements of right ventricular ejection fraction, using radionuclide ventriculography, and pulmonary arterial pressure. There was, however, a weak but significant correlation between right ventricular ejection fraction and the pulmonary vascular resistance (r = 0.40, p<0.005). In 52 of these patients, 37 with pulmonary hypertension, right ventricular end-systolic volume index was 53 ± 21 ml·m–2and end-diastolic volume index was 86 ± 27 ml·m–2, compared with a calculated mean of 33 ml·m–2and 79 ml·m–2, respectively, for normal subjects. In 24 of these patients where the measurements were made at rest and on exercise, the mean right ventricular end-systolic volume increased from 66 ± 20 ml·m–2to 87 ± 32 ml·m–2, with an increase in right ventricular systolic pressure from 28 ± 9 mm Hg to 55 ± 15 mm Hg. Analysis of the slope of the right ventricular end-systolic pressure volume relationship at rest and on exercise suggested relatively normal right ventricular contractility in the majority of patients. Thus, in these patients with stable COPD, despite the presence of pulmonary hypertension, right ventricular contractility remained relatively normal. (Chest 1988; 94:1169-75)

Published
1988
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15. Brain Natriuretic Peptide Measurement in Patients With COPD and Cardiovascular Disease.

Author

Kheir, Fayez, Salerno, Daniel A., Maclay, John D., and MacNee, William

Subjects
CARDIOVASCULAR diseases, OBSTRUCTIVE lung diseases, DISEASES, HEART diseases, LUNG diseases
Abstract

Several letters to the editor are presented in response to articles in previous issues including "Cardiovascular Disease in COPD: Mechanisms," in the March 2013 issue and the response by the authors to the said letter to the editor.

Published
2013
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