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2. Surfactant Protein-D and Surfactant Inhibit Endotoxin-Induced Pulmonary lnflammation.

Author

Ikegami, Machiko, Scoville, Elizabeth A., Grant, Shawn, Korfhagen, Thomas, Brondyk, William, Scheule, Ronald K., and Whitsett, Jeffrey A.

Subjects
ENDOTOXINS, LUNG diseases, INFLAMMATION, RECOMBINANT proteins, RESPIRATORY diseases
Abstract

The article reports on the results of a study of the effect of exogenous recombinant human surfactant protein-D (rhSP-D) on protection of the adult mouse lung from lipopolysaccharide (LPS)-induced and lipoteichoic acid (LTA)-induced injury. A description of study methods is presented. The study concluded that intratracheal rhSP-D inhibited inflammation induced by intratracheal LPS and LTA instillation in the lung.

Published
2007
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