1. Double infection of the CNS with herpes simplex and mumps viruses. Serological and ultrastructural studies
- Author
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Celso Cruz, Manuel M. Paula-Barbosa, Carlos Alberto Silva, Maria Fernanda Ferreira, and Maria Edite Rio
- Subjects
Male ,Pathology ,medicine.medical_specialty ,viruses ,Neuropathology ,Mumps virus ,medicine.disease_cause ,Antibodies, Viral ,Serology ,medicine ,Humans ,Child ,Mumps ,medicine.diagnostic_test ,business.industry ,Brain biopsy ,Complement Fixation Tests ,Herpes Simplex ,General Medicine ,medicine.disease ,Virology ,Double infection ,Frontal Lobe ,Microscopy, Electron ,Herpes simplex virus ,Pediatrics, Perinatology and Child Health ,Ultrastructure ,Encephalitis ,Neurology (clinical) ,business - Abstract
Clinical, serological and ultrastructural features are described in a case of acute encephalitis. The ultrastructural study of brain biopsy specimens revealed herpes-and paramyxovirus-like particles in neurons and glial cells that were characterized as herpes simplex and mumps viruses by serological study in serum and CSF. Of the few cases previously reported with double encephalitis, this is the only one in which ultrastructural and serological evidence of combined brain infection has been found.
- Published
- 1985