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4. Neurodevelopmental Disorders, Schizophrenia Spectrum Disorders and Catatonia: The "Iron Triangle" Rediscovered in a Case Report.

Author

Fantozzi, Pamela, Del Grande, Claudia, Berloffa, Stefano, Tolomei, Greta, Salluce, Carmen, Narzisi, Antonio, Salarpi, Gianluca, Capovani, Barbara, and Masi, Gabriele

Subjects
THERAPEUTIC use of lithium, DIAGNOSIS of schizophrenia, DIAGNOSIS of autism, SUBSTANCE abuse, ELECTROCONVULSIVE therapy, CATATONIA, CHILD psychopathology, MENTAL depression, CLASSIFICATION of mental disorders, EMOTION regulation, ANTIPSYCHOTIC agents, VALPROIC acid, GABAPENTIN, TRANQUILIZING drugs, SYMPTOMS, ADOLESCENCE
Abstract

Catatonia is a complex neuropsychiatric syndrome, occurring in the context of different psychiatric and neurodevelopmental disorders, in neurological and medical disorders, and after substance abuse or withdrawal. The relationship between Autism Spectrum Disorder (ASD), Schizophrenia Spectrum Disorders (SSDs) and catatonia has been previously discussed, with the three disorders interpreted as different manifestations of the same underlying brain disorder (the "Iron Triangle"). We discuss in this paper the diagnostic, clinical and therapeutic implications of this complex relationship in an adolescent with ASD, who presented an acute psychotic onset with catatonia, associated with mixed mood symptoms. Second-generation antipsychotics were used to manage psychotic, behavioral and affective symptoms, with worsening of the catatonic symptoms. In this clinical condition, antipsychotics may be useful at the lowest dosages, with increases only in the acute phases, especially when benzodiazepines are ineffective. Mood stabilizers with higher GABAergic effects (such as Valproate and Gabapentin) and Lithium salts may be more useful and well tolerated, given the frequent association of depressive and manic symptoms with mixed features. [ABSTRACT FROM AUTHOR]

Published
2023
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5. Internet Gaming Disorder in Children and Adolescents with Attention Deficit Hyperactivity Disorder

Author

Berloffa, Stefano, primary, Salvati, Andrea, additional, D’Acunto, Giulia, additional, Fantozzi, Pamela, additional, Inguaggiato, Emanuela, additional, Lenzi, Francesca, additional, Milone, Annarita, additional, Muratori, Pietro, additional, Pfanner, Chiara, additional, Ricci, Federica, additional, Ruglioni, Laura, additional, Tacchi, Annalisa, additional, Tessa, Chiara, additional, Villafranca, Arianna, additional, and Masi, Gabriele, additional

Published
2022
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6. Treatment with Methylphenidate Improves Affective but Not Cognitive Empathy in Youths with Attention-Deficit/Hyperactivity Disorder

Author

Fantozzi, Pamela, primary, Muratori, Pietro, additional, Caponi, Maria Celeste, additional, Levantini, Valentina, additional, Nardoni, Cristina, additional, Pfanner, Chiara, additional, Ricci, Federica, additional, Sesso, Gianluca, additional, Tacchi, Annalisa, additional, Milone, Annarita, additional, and Masi, Gabriele, additional

Published
2021
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