1. The Management of Asymptomatic Congenital Pulmonary Airway Malformation: Results of a European Delphi Survey
- Author
-
Casper M. Kersten, Sergei M. Hermelijn, Dhanya Mullassery, Nagarajan Muthialu, Nazan Cobanoglu, Silvia Gartner, Pietro Bagolan, Carmen Mesas Burgos, Alberto Sgrò, Stijn Heyman, Holger Till, Janne Suominen, Maarten Schurink, Liesbeth Desender, Paul Losty, Henri Steyaert, Suzanne Terheggen-Lagro, Martin Metzelder, Arnaud Bonnard, Rony Sfeir, Michael Singh, Iain Yardley, Noor R. V. M. Rikkers-Mutsaerts, Cornelis K. van der Ent, Niels Qvist, Des W. Cox, Robert Peters, Michiel A. G. E. Bannier, Lucas Wessel, Marijke Proesmans, Michael Stanton, Edward Hannon, Marco Zampoli, Francesco Morini, Harm A. W. M. Tiddens, René M. H. Wijnen, Johannes M. Schnater, Paediatric Pulmonology, Institut Català de la Salut, [Kersten CM, Hermelijn SM] Department of Pediatric Surgery, Erasmus MC Sophia Children’s Hospital, Rotterdam, The Netherlands. [Mullassery D, Muthialu N] Department of Pediatric Surgery, Great Ormond Street Hospital, London, UK. [Cobanoglu N] Department of Pediatric Pulmonology, Ankara University School of Medicine, Ankara, Turkey. [Gartner S] Unitat de Pneumologia Pediàtrica i Fibrosi Quística, Vall d’Hebron Hospital Universitari, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus, Kindergeneeskunde, MUMC+: MA Medische Staf Kindergeneeskunde (9), RS: FHML non-thematic output, Pediatrics, Pediatric Surgery, and Radiology & Nuclear Medicine
- Subjects
técnicas de investigación::métodos::diseño de la investigación [TÉCNICAS Y EQUIPOS ANALÍTICOS, DIAGNÓSTICOS Y TERAPÉUTICOS] ,congenital lung abnormalities ,congenital pulmonary airway malformation ,core outcome set ,outcome parameters ,consensus ,CYSTIC ADENOMATOID MALFORMATION ,INFANTS ,CHILDREN ,LOBECTOMY ,Pediatrics ,ARGUMENT ,POSTNATAL MANAGEMENT ,Investigative Techniques::Methods::Research Design [ANALYTICAL, DIAGNOSTIC AND THERAPEUTIC TECHNIQUES, AND EQUIPMENT] ,Medicine and Health Sciences ,MANAGEMENT ,POSTNATAL ,LUNG MALFORMATIONS ,PREDICTORS ,Science & Technology ,LESIONS ,Presa de decisions ,NATURAL-HISTORY ,Reconstructive and regenerative medicine Radboud Institute for Health Sciences [Radboudumc 10] ,Pulmons - Malalties ,Ciencias de la información::análisis de sistemas::técnica Delfos [CIENCIA DE LA INFORMACIÓN] ,Respiratory Tract Diseases::Lung Diseases [DISEASES] ,Pediatrics, Perinatology and Child Health ,Information Science::Systems Analysis::Delphi Technique [INFORMATION SCIENCE] ,Malalties congènites ,enfermedades respiratorias::enfermedades pulmonares [ENFERMEDADES] ,Life Sciences & Biomedicine - Abstract
Anomalías pulmonares congénitas; Consenso; Parámetros de resultado Anomalies pulmonars congènites; Consens; Paràmetres de resultat Congenital lung abnormalities; Consensus; Outcome parameters Consensus on the optimal management of asymptomatic congenital pulmonary airway malformation (CPAM) is lacking, and comparison between studies remains difficult due to a large variety in outcome measures. We aimed to define a core outcome set (COS) for pediatric patients with an asymptomatic CPAM. An online, three-round Delphi survey was conducted in two stakeholder groups of specialized caregivers (surgeons and non-surgeons) in various European centers. Proposed outcome parameters were scored according to level of importance, and the final COS was established through consensus. A total of 55 participants (33 surgeons, 22 non-surgeons) from 28 centers in 13 European countries completed the three rounds and rated 43 outcome parameters. The final COS comprises seven outcome parameters: respiratory insufficiency, surgical complications, mass effect/mediastinal shift (at three time-points) and multifocal disease (at two time-points). The seven outcome parameters included in the final COS reflect the diversity in priorities among this large group of European participants. However, we recommend the incorporation of these outcome parameters in the design of future studies, as they describe measurable and validated outcomes as well as the accepted age at measurement.
- Published
- 2022