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The dislocation between regional innovation and economic development directly influences the economic effect of regional innovation. However, no in-depth researches have been made on how to solve this problem. Using data from Henan Province, China, employing geographical detector technology, this paper focuses on testing whether the industry-university-research cooperation can contribute to coordinating the relation between regional innovation and economic development. It is shown that: 1) the industry-university-research cooperation in Henan Province is increasing gradually, and the network presents a core-edge structure, and the coupling degree between regional innovation and economic development is spatially unbalanced, which is similar to the spatial distribution of the intensity of industry-university-research cooperation; 2) as an important approach to effectively connect scientific researches with market demands, the industry-university-research cooperation can help form an interactive, interconnected, coupled and coordinated virtuous relation between regional innovation and economic development. Compared with the cooperation between organizations of the same type and the separate innovation of organizations, the improvement of the industry-university-research cooperation level can better coordinate the relation between regional innovation and economic development; 3) the cooperative innovation model between enterprises and universities can better promote the coupling between regional innovation and economic development, compared with many industry-university-research cooperation models. For underdeveloped areas lacking local knowledge base, industry-university-research cooperation should be considered as a long-term development strategy, especially using the knowledge sources of external universities and scientific research institutions to enhance innovation capability and achieve economic growth. [ABSTRACT FROM AUTHOR]

Since China's reform and opening up in 1978, the acceleration of industrialization and urbanization in China had led to dramatic changes in the pattern of urban-rural land use. In this paper, we focused on the rural industrialized areas in central China (Xinxiang County and Changyuan City of Henan Province). We used the average nearest neighbor index, spatial statistical analysis, and a structural equation model to analyze the spatiotemporal evolution and influencing factors of urban-rural construction land based on multi-source spatial data and survey data. The results showed that: 1) from 1975 to 2019, the spatial distribution of urban-rural construction land in rural industrialized areas had evolved from homogeneous distribution to local agglomeration. In terms of comparative analysis of cases, the spatial distribution of urban-rural construction land in Changyuan City had shown a trend from diffusion to agglomeration, and Xinxiang County had overall shown a spatial change from homogenization to agglomeration and then to regional integration development. 2) The hot spots with increased urban-rural construction land significantly expanded, and they had a high degree of spatial overlap with industrial development. Among them, Xinxiang County was concentrated in central and marginal areas, and Changyuan was mainly concentrated in central urban areas. 3) From the evolution of spatial proximity of urban-rural construction land, rural industrialized areas generally decline, showing the characteristics of internal differentiation in the rate of change. 4) Industrial development, social economy, the policy environment, and urban development played a positive role in promoting the expansion of urban-rural construction land in rural industrialized areas. To promote the optimal use of regional land and the integrated development of urban-rural areas, we should combine the advantages of regional endowment, formulate development strategies according to local conditions, and adjust the way that land is used in a timely manner. [ABSTRACT FROM AUTHOR]