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Abstract: Aim: To study the chemical constituents from the roots of Derris elliptica (Roxb.) Benth. Methods: The chemical constituents were isolated by various chromatographic methods, and the chemical structures were elucidated on the basis of spectral analysis. Result: Four lipid constituents were obtained, including three ceramides, (2S, 3S, 4R, 8E)-2N-[(2′R, 3′)-2′, 3′-dihydroxyhexacosanoyl]-1, 3, 4-trihydroxy-8-octadecene (1), (2S, 3S, 4R, 8E)-2N-[(2′R)-2′-hydroxyhexacosanoyl]-1, 3, 4-trihydroxy-8-octadecene (2), 1-O−β-D-glucopyranosyl-(2S, 3S, 4R, 8E)-2N-[(2′R)-2′-hydroxytetracosanoyl]-3, 4-dihydroxy-8-octadecene (3), and a poly-hydroxyl octadecenoic acid, 12, 13, 15-trihydroxy-9-octadecenoic acid (4). Conclusion: Compound 1 is a novel ceramide with hydroxyl group at C-3′, and is the first occurrence of ceramides with hydroxyl group at C-3′. Compounds 2–4 were isolated from genus Derris for the first time. [Copyright &y& Elsevier]

Abstract: Aim: To study the chemical constituents of Derris elliptica (Roxb.) Benth. Methods: The chemical constituents were isolated by various chromatographic methods, and the chemical structures were elucidated on the basis of spectral analysis. Results: Seven rotenoids were obtained and their structures were identified as 7′-hydroxy-6a, 12a-dehydrodeguelin (1), 6-hydroxy-6a, 12a-dehydrodeguelin (2), (6aR, 12aR, 4′R, 5′S)-4′, 5′-dihydro-4′, 5′-dihydroxytephrosin (3), 6′-hydroxy-6a, 12a- dehydrorotenone (4), (-)-rotoic acid (5), (-)-deguoic acid (6), 12-deoxo-12α-acetoxyelliptone (7). Conclusions: Compound 1 is a new compound, compounds 2-6 were isolated from this genus for the first time, and compound 7 was isolated from Derris elliptica (Roxb.) Benth. for the first time. [Copyright &y& Elsevier]