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Investigates the difference of rejection in single versus combined pancreas and kidney transplantation in rats. Mean survival time of pancreas in simultaneous pancreas and kidney transplant and in pancreas alone; Suggestion that different organs differ in immunoallergenization and immunoregulation; Effectiveness of cyclosporine A in prolonging the MST of pancreas and kidney.

Objective. To investigate the cold preservation effect of rat livers by modified storage method with self-made HYD solution. Methods. The modified method was that the vascular bed of rat livers was expanded with an additional 20 to 40ml self-made HYD solution/100g liver. After removing the liver, the extra HYD solution expressed as % liver weight was entrapped via portal infusion by tying off the supra-and infra hepatic inferior vena cava. According to the amount of extra HYD solution, 40 rats were randomly divided into four groups including: control group with conventional storage method, 20% group, 30% group and 40% group. The preservation effect of modified storage method with that of conventional storage method by using isolated perfused rat liver model was compared. Results. Bile production and all the indices of hepatic microcirculation including portal perfusion pressure, endothelin-1 in the effluent, trypan blue distribution time and histology in modified method groups were significantly superior to those in control group (P < 0.05). The liver enzymes in 30% group was the best among the modified method groups. Conclusion. The modified cold storage method is effective and may have potential for clinical application for liver preservation. [ABSTRACT FROM AUTHOR]

Examines the effectiveness of spleen transplantation for hemophilia A in China. Suitability of the transplantation for perfusion and preservation of spleen; Examination on the efferent fluids from the splenic vein; Observations of morphological changes in extracorporeal spleen.

Investigates the effects of cold preservation on rat fatty liver. Changes of portal perfusion pressure; Enzymes release in the effluent; Mortality of sinusoid lining cell.