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Micro-sensors are fabricated by co-electrospinning InO and SnO nanofibers on the substrates of SiO/Si with interdigitated Pt signal electrodes. The total sensor area is 1.36 mm × 0.55 mm and the active area is only 0.63 mm × 0.55 mm. Excellent NH sensing properties are obtained based on the sensors at room temperature. The sensitivity is at most 28 when the sensors are exposed to NH of 10 ppm. The response time is 8 s or so and the recovery time is nearly 2 s. Not only fine selectivity, but also long-time stability is obtained. The results not only demonstrate the obtained micro-sensors are very promising devices for NH detection, but also show a possible route for large-scale NH sensor fabrication at the industrial level. [ABSTRACT FROM AUTHOR]

As a newly identified transcription factor in Candida albcians, CaSfl1 has been shown to be involved in cell flocculation and filamentation and in the negative regulation of several genes involved in hyphal growth. In this study, we constructed Casfl1Δ/Δ mutants and confirmed that deletion of this gene indeed affected cell flocculation and filamentation. In addition, by RT-PCR we found that while Casfl1 repressed the expression of several hypha-specific genes including HWP1, ECE1, ALS1, ALS3, and FLO8, it strongly activated the expression of the heat-shock protein genes HSP30 and HSP90 under certain stress conditions. Therefore, we propose that CaSfl1 can act as both positive and negative regulators, thereby playing a dual role in transcriptional controls in Candida albicans. [ABSTRACT FROM AUTHOR]