1. Arrhythmias in Cardiac Sarcoidosis Bench to Bedside
- Author
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Clifford V. Harding, Syed Quadri, Francis Murgatroyd, Mina K. Chung, Konstantinos C. Siontis, David H. Birnie, Davendra Mehta, Thomas Crawford, Jagmeet P. Singh, Logan Vincent, Paul Leis, Christine Jellis, Frank Bogun, Lavanya Bellumkonda, Ashley Bock, Peter Zimetbaum, Johan Grunewald, Christopher Maulion, Edward J. Miller, Jordana Kron, Marc A. Judson, Richard Cheng, Timm Dickfeld, Kenneth A. Ellenbogen, Jerry D. Estep, Edwin T. Zishiri, Ben A. Lin, Jose A. Joglar, Ron Blankstein, Pavan Bhat, Thomas Callahan, Steven Kalbfleish, Lynda E. Rosenfeld, Elizabeth S. Kaufman, Jason Appelbaum, William H. Sauer, Paul Cremer, Daniel A. Culver, Deborah H Kwon, Kristen K. Patton, Paolo Spagnolo, David R. Okada, Jonathan Chrispin, and Maryjane Farr
- Subjects
Bradycardia ,Tachycardia ,medicine.medical_specialty ,Sarcoidosis ,heart failure ,Disease ,Arrhythmias ,030204 cardiovascular system & hematology ,tachycardia ,bradycardia ,Article ,defibrillator ,03 medical and health sciences ,0302 clinical medicine ,Heart Conduction System ,Heart Rate ,Cardiac magnetic resonance imaging ,Physiology (medical) ,medicine ,Humans ,atrial fibrillation ,030212 general & internal medicine ,Intensive care medicine ,medicine.diagnostic_test ,sarcoidosis ,Arrhythmias, Cardiac ,Cardiomyopathies ,business.industry ,Atrial fibrillation ,medicine.disease ,Positron emission tomography ,Heart failure ,cardiovascular system ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business ,Cardiac - Abstract
Cardiac sarcoidosis is a component of an often multiorgan granulomatous disease of still uncertain cause. It is being recognized with increasing frequency, mainly as the result of heightened awareness and new diagnostic tests, specifically cardiac magnetic resonance imaging and18F-fluorodeoxyglucose positron emission tomography scans. The purpose of this case-based review is to highlight the potentially life-saving importance of making the early diagnosis of cardiac sarcoidosis using these new tools and to provide a framework for the optimal care of patients with this disease. We will review disease mechanisms as currently understood, associated arrhythmias including conduction abnormalities, and atrial and ventricular tachyarrhythmias, guideline-directed diagnostic criteria, screening of patients with extracardiac sarcoidosis, and the use of pacemakers and defibrillators in this setting. Treatment options, including those related to heart failure, and those which may help clarify disease mechanisms are included.
- Published
- 2021