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Background: Self-reported short and long sleep duration have been associated with adverse cardiometabolic health outcomes in laboratory and epidemiologic studies, but interpretation of such data has been limited by methodological issues. Methods: We analyzed adult 2007-2008 US National Health and Nutrition Examination Survey (NHANES) data (N=5,649). Average self-reported nightly sleep duration was reported and categorized as either very short (<5h), short (5-6h), normal (7-8h), or long (=9h). Self-reported as well as objective evidence of obesity, diabetes, hypertension, and hyperlipidemia were recorded. Univariate comparisons were conducted across sleep duration categories for all variables. Binary logistic regression analyses were performed using cardiometabolic factor as the outcome variable, and sleep duration category as the predictor variable, before and after adjusting for age, sex, race/ethnicity, acculturation, education, access to insurance, food security, home ownership, smoking, and caffeine use. Results: See table. In adjusted analyses, very short sleep was associated with selfreported hypertension, self-reported hyperlipidemia, objective hyperlipidemia, self-reported diabetes, and objective obesity. Regarding short sleep (5-6hrs), in adjusted analyses, elevated risk was seen for self-reported hypertension selfreported obesity and objective obesity. Regarding long sleep (=9hrs), no elevated risk was found for any outcomes. Conclusions: Very short and short sleep duration are associated with self-reported and objectively-determined adverse cardiometabolic outcomes, even after adjustment for covariates. [ABSTRACT FROM AUTHOR]

Introduction: Insufficient sleep is associated incident hypertension. Because blood pressure (BP) varies across 24h, shorter sleep may be associated with increased BP across all 24h. Additionally, we evaluated whether BP variability was also associated with shorter sleep. Methods: Participants were adults with untreated prehypertension or stage-1 hypertension assessed at baseline as part of a clinical trial. Recordings took place during overnight visits in a Clinical Research Center. Sleep was reported by nurses continuously monitoring patients. Those with <7h sleep were classified "shorter" (N=13) and the rest "longer" (N=30). BP was assessed with a Spacelabs ambulatory monitor. Linear regression models evaluated effect of group on day, night, and 24h systolic and diastolic BP and heart rate (HR). Results: The "shorter" group slept for M=370 (SD=87) minutes and the "longer" group slept for M=521 (SD=51) mins. Results for day, night, and 24h systolic and diastolic blood pressure and heart rate are reported in the Table. Also, higher 24h variability in systolic BP (B=1.2, p=0.03), diastolic BP (B=1.4, p=0.002), and HR (B=1.3, p=0.03) were demonstrated. This was reflected in higher variability during daytime for systolic BP (B=1.1, p=0.04), diastolic BP (B=1.5, p=0.001), and HR (B=1.2, p=0.05); no differences in variability were seen during the night. Conclusions: Shorter sleep duration is associated with higher systolic BP and HR across 24h (day and night), as well as increased variability in systolic and diastolic BP and HR across 24h (during the day in particular). This could provide additional insight in to how sleep duration is associated with hypertension incidence. [ABSTRACT FROM AUTHOR]