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The article presents subject index for the journal "Clinical and Experimental Immunology." Some of the subjects included are: Allergen antibodies, a modified radioallergosorbent test for the in vitro detection of, 617; Anaemia, autoimmune haemolytic; Chromium survival studies in patients with different kinds of warm autoantibodies, 559; Antibodies and anti-kidney antibodies in kidney transplanted patients and patients with renal disease, occurrence and cross-reactivity of heterophile, 191; Antibodies to tubercle bacilli in sera from non-tuberculous and tuberculous individuals. Universal occurrence of, 65; Antilymphocyte globulin by human peripheral lymphocytes, uptake of, 423.

By means of the antigen-antibody crossed electrophoresis of Laurel! twenty-two different candida albicans precipitins were demonstrated in a serum from a 56-year-old woman suffering from idiopathic hypoparathyroidism and chronic candidiasis. This precipitin response is remarkably strong, but a detailed evaluation of the finding must await further investigations. lt is mentioned how the human precipitins may be quantitated and the titres expressed in arbitrary rabbit precipitin units. The antigen-antibody crossed electrophoresis may be useful in other infections, and possibly in certain autoimmune diseases, in order quantitatively to screen patient sera for a multitude of precipitins without purification of the individual antigens. [ABSTRACT FROM AUTHOR]

A method for determining the antigen-binding activities of specific immunoglobulins in serum is described. Samples of sera were applied to commercial immunodiffusion plates and unprecipitated proteins eluted. The precipitate circles were challenged with specific radio-labelled antigen and exposed to X-ray film. Blackened circles on the radioautograph were found to be good indices of the antigen-binding activity of each immunoglobulin and could be monitored using a Beckman Model R Analytrol. The height of each analytrol peak provided an objective estimate of the intensity of darkening. Variation in the amount of added radio-antigen had a direct effect upon the intensity of the darkened circle at low concentrations. At a given concentration of antigen, however, all antigen-binding sites became saturated and additional increases in antigen concentration did not further increase the density of blackening. The quantity of antigen required to just saturate the combining sites of a particular immunoglobulin is a measure of the antigen-binding activity of that immunoglobulin. The employment and some of the applications of this relatively simple radio-isotopic technique are discussed. [ABSTRACT FROM AUTHOR]

The article presents a list of abbreviations related to immunology. Some of the abbreviation given are for antibody, antigen, acid-citrate-dextrose, autoimmune complement fixation, antilymphocyte globulin, bis-diazotized benzidine, biological false positive reaction, bovine gammaglobulin, bovine serum albumin, Bence-Jones, buffered saline solution, carboxymethyl, cerebrospinal fluid, diethylaminoethyl, deoxyribonucleic acid, dinitrochlorbenzenc, ethylenediamine tetracetic acid, erythrocyte sedimentation rate, fluorescein to protein, gonococeal complement fixation test, graft versus host, intraperitoneal, intravenous, keyhole limpet haemocyanin, long acting thyroid stimulator, lymphocytic choriomeningitis, lupus erythematosus and so on.

The article presents a list of abbreviations that have been used in the September 1, 1971 issue of the periodical "Clinical and Experimental Immunology." The abbreviation "Ab" is used for antibody; "Ag" is used for antigen; "ACD" is used for acid-citrate-dextrose; "AICF" is used for autoimmune complement fixation; "ALG" is used for antilymphocyte globulin; "HSA" is used for human serum albumin; "IF" is used for intrinsic factor; "IFT" is used for immunofluorescence technique; "DNA" is used for deoxyribonucleic acid; "DNCB" is used for dinitrochlorbenzene; etc.