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Lipid metabolism is elevated in cancer to satisfy increased energy demands.2 Considering APOC2's known function in FA transport and metabolism, its upregulation is a plausible mechanism for cancer adaptation and growth. APOC2, cancer, lipid metabolism Keywords: APOC2; cancer; lipid metabolism EN APOC2 cancer lipid metabolism 1 5 5 07/01/21 20210601 NES 210601 Abbreviations AML acute myeloid leukemia APOC2 apolipoprotein C2 FA fatty acid OS overall survival Dear Editor, Apolipoprotein C2 (APOC2), an activator of lipoprotein lipase, participates in hydrolysis of triglycerides, very low-density lipoproteins, and high-density lipoproteins to release free fatty acids (FA).1 FA oxidation has emerged as an important source of energy for cancer survival and growth.2 Patterns of I APOC2 i genomics and transcriptomic alterations in cancer remained unexplored. [Extracted from the article]

Aplastic anaemia, cytokine-induced memory-like NK cell, natural killer cells, single-cell RNA sequencing We didn't detect NCAM (CD56) in the dataset and used CD7/KLRD1/KLRF1/NGK7/GNLY as specific NK cell markers.[3] As expected, all these eight clusters expressed high levels of NK cell-specific markers (Figure 1B). Keywords: aplastic anaemia; cytokine-induced memory-like NK cell; natural killer cells; single-cell RNA sequencing EN aplastic anaemia cytokine-induced memory-like NK cell natural killer cells single-cell RNA sequencing 1 6 6 12/29/22 20221201 NES 221201 Dear Editor, In recently, we reported the important contribution of nature killer (NK) cells in the pathogenesis of severe aplastic anaemia (SAA). (B) LogFC bar graph of DEGs identified in NK cells by comparing HC-BM cells with HC-PB cells. [Extracted from the article]