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Dear Editor Diabetes mellitus (DM) has become a significant chronic condition that seriously affects human health.[1] Nowadays, China has become the country with the largest number of DM patients worldwide, of which more than 90% are type 2 diabetes mellitus (T2DM).[2] The increasing prevalence of DM exacerbates the incidence of end-stage renal disease (ESRD).[3] T2DM-related ESRD not only reduces survival rate and health-related quality of life but also places a significant cost on patients as well as society.[[4], [6]] To identify clinical predictive factors and develop prediction models for ESRD risk in T2DM patients, we used the study population extracted from the China Renal Data System, a database containing the information of more than seven million patients attended at 19 hospitals in the Chinese mainland, as previously described.[7] ESRD, including an eGFR of 15 mL/min/1.73 m SP 2 sp or less, or the commencement of dialysis or kidney transplantation due to ESRD, was classified as the outcome. These prediction models were further provided as simple bedside tools, including a risk score and a nomogram, which could be extensively applied to assess T2DM patients' ESRD risk in clinical practice, to aid clinical decision-making and sensible resource allocation. Using a randomized approach, 55 824 patients with T2DM from 10 medical centers were included in the derivation cohort, and 25 745 patients from seven additional medical institutions were included for external validation. [Extracted from the article]