1. Pure red-cell aplasia and autoimmune hemolytic anemia in a patient with acute hepatitis A
- Author
-
Tae Hoon Oh, Dong Hyun Sinn, Tae Joo Jeon, Won Chang Shin, Sung Gyun Cho, Hyo Jeong Chang, and Won Choong Choi
- Subjects
Adult ,Male ,medicine.medical_specialty ,Antineoplastic Agents, Hormonal ,Anemia ,Prednisolone ,Pure red cell aplasia ,Case Report ,Red-Cell Aplasia, Pure ,urologic and male genital diseases ,Gastroenterology ,Young Adult ,Bone Marrow ,hemic and lymphatic diseases ,Internal medicine ,medicine ,Humans ,lcsh:RC799-869 ,Autoimmune hemolytic anemia ,Molecular Biology ,health care economics and organizations ,Hepatology ,medicine.diagnostic_test ,business.industry ,Pure red-cell aplasia ,Hepatitis A ,Middle Aged ,medicine.disease ,Treatment Outcome ,medicine.anatomical_structure ,Acute Disease ,Immunology ,Female ,lcsh:Diseases of the digestive system. Gastroenterology ,Anemia, Hemolytic, Autoimmune ,Hemoglobin ,Bone marrow ,business ,Liver function tests ,medicine.drug - Abstract
Pure red cell aplasia (PRCA) and autoimmune hemolytic anemia (AIHA) have rarely been reported as an extrahepatic manifestation of acute hepatitis A (AHA). We report herein a case of AHA complicated by both PRCA and AIHA. A 49-year-old female with a diagnosis of AHA presented with severe anemia (hemoglobin level, 6.9 g/dL) during her clinical course. A diagnostic workup revealed AIHA and PRCA as the cause of the anemia. The patient was treated with an initial transfusion and corticosteroid therapy. Her anemia and liver function test were completely recovered by 9 months after the initial presentation. We review the clinical features and therapeutic strategies for this rare case of extrahepatic manifestation of AHA.
- Published
- 2014
- Full Text
- View/download PDF