1. Serum procalcitonin at the time of admission to the ICU as a predictor of short-term mortality.
- Author
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Meng FS, Su L, Tang YQ, Wen Q, Liu YS, and Liu ZF
- Subjects
- APACHE, C-Reactive Protein analysis, Calcitonin Gene-Related Peptide, Critical Illness mortality, Demography, Female, Humans, Male, Middle Aged, Prognosis, ROC Curve, Sepsis blood, Sepsis microbiology, Survival Analysis, Time Factors, Treatment Outcome, Calcitonin blood, Intensive Care Units statistics & numerical data, Patient Admission, Protein Precursors blood, Sepsis mortality
- Abstract
Objective: This purpose of this study was to determine if serum procalcitonin (PCT) concentration at the time of admission to the ICU is a predictor of all-cause short-term mortality., Design and Methods: This prospective cross-sectional study was conducted over a 16-month period with 86 consecutive critically ill patients. The semi-quantitative PCT-Q test was performed and APACHE II scores and C-reactive protein (CRP) concentrations were determined within 24 h of admission., Results: PCT-Q test value was a better predictor of all-cause short-term mortality than CRP value or APACHE II score. PCT > or = 10 ng/mL was highly and independently correlated with mortality. Use of PCT-Q > or = 10 ng/mL was superior to use of APACHE II > or = 25 or CRP > or = 10 mg/dL as a predictor of poor outcome., Conclusions: A PCT-Q value > or = 10 ng/mL obtained at the time of admission to the ICU is a strong predictor of short-term mortality.
- Published
- 2009
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