1. P52: Solitary bone plasmacytoma: Diagnostic and therapeutic management and evolutive aspects.
- Author
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Benmoussa, R., Majdoul, S., Touil, N., Kacimi, O., Chikhaoui, N., Benchakroun, N., Jouhadi, H., Tawfik, N., Sahraoui, S., and Benider, A.
- Subjects
PLASMACYTOMA ,BONE tumors ,TUMOR treatment - Abstract
Objectives: To report the experience of Ibn Rochd oncology center on management of solitary bone plasmacytoma. Describe the radiological findings in bone solitary plasmacytoma throughout plain radiographs, CT and MRI. Methods: Ten cases of solitary bone plasmacytoma were collected retrospectively in the Ibn Rushd-oncology center over a period of 8 years. Results: The mean age was 57 years old (range 48-68) and the mean consulting time about 8 months (range 4-24). The plasmacytoma was vertebral in six cases, in the pelvis in two, in a maxillary sinus in one, and in the cranial vault in one case. The most common primary clinical signs were pain and neurological disorders. The diagnosis was based on imaging data (plain radiographs, CT and MRI) and histological examination of bone biopsy. A research assessment for multiple myeloma was achieved in all cases and found normal. Radiotherapy graded 40 to 45 Gy was delivered in ten patients. Decompressive laminectomy was performed in four patients. After the end of treatment, there has been a regression of pain in eight patients and recovery of neurological disorders in half. Conclusion: Solitary bone plasmacytoma is a malignant tumor developed from plasmocyte cells. Its diagnosis is retained after a looking for a negative multiple myeloma. The basic treatment of solitary plasmacytoma bone is radiotherapy, which provides the best local control. Surgery is useful only in cases of nerve compression or bone instability. [ABSTRACT FROM AUTHOR]
- Published
- 2015