1. Epidemiological characteristics, management, and outcomes of atrial fibrillation in <scp>TUNISIA</scp> : Results from the National Tunisian Registry of Atrial Fibrillation ( <scp>NATURE‐AF</scp> )
- Author
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Wejdene Wechtati, Wafa Fehri, Oussema Ben Rejab, Leila Riahi, Ali Neji, Feriel Baraket, Majed Hassine, Wacef Ayadi, Foued Azzouzi, Jawher Zemni, Rachid Mechmeche, Sofiene Kammoun, Monia Jammali, Emna Allouche, Khaled Sayahi, Mahmoud Cheikh Bouhlel, Habib Gamra, Rym Jemli, Rim Chrigui, Sanaa Islem, Mohamed Ali Meghaieth, Rawdha Othmani, Med Ali Azaiez, Kais Battikh, Hajer Rekik, Saoussen Antit, Tarek Najar, Sondes Kraiem, Iheb Chahbani, Riadh Garbaa, Manel Ben Halima, Salem Kachboura, Faouzi Addad, Rafik Chettaoui, Ikram Kammoun, Wissem Sdiri, Dorra Mbarek, Syrine Abid, Ali Ben Khalfallah, Mohamed Hmem, Sonia Chabrak, Khadija Mzoughi, Samir Kammoun, Slim Kacem, Soraya Ben Youssef, Khaled Ben Jemaa, Afef Ben Halima, Meriem Drissa, Mbarek Mohamed Ben, Hanene Charfeddine, Sami Braham, Wajih Smati, Habiba Drissa, Sami Milouchi, Amel Ouerghi, Zeynab Jebbari, Essia Boughzela, Sandrine Haidar, Salem Abdesselem, Mehdi Ben Miled, Sana Ouali, Hassen Ajmi, Malek Mezri, Rami Tlili, Leila Abid, Anissa Gharbi, Ridha Ennouri, Sonia Marrakchi, Faouzi Maatouk, Lilia Zakhama, Ali Guesmi, Mourad Jarrar, Mokdad Ayari, Sihem Heraiech, Habib Bousadia, Mariem Ben Romdhane, Hamda Zaghdoudi, Karim Ben Brahim, Leila Bezdah, Taha Ounissi, Hela Naanea, Wided Nasraoui, Basma Trimech, Gouider Jridi, Salma Krichane, Selma Charfeddine, Anissa Joulak, Larbi Noureddine, Abdeddayem Haggui, Moufid Hadrich, Karim Zoughi, Wassim Brahim, Fehmi Abbes Mohamed, Mohamed Sami Mourali, Leila Hached, Samir Tlili, Samira Kaabachi, and Nabil Hamrouni
- Subjects
Male ,medicine.medical_specialty ,Tunisia ,Antithrombotic Agent ,medicine.medical_treatment ,Clinical Investigations ,Context (language use) ,030204 cardiovascular system & hematology ,Antiarrhythmic agent ,outcomes ,Amiodarone ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Internal medicine ,Atrial Fibrillation ,Epidemiology ,medicine ,Humans ,Prospective Studies ,Registries ,030212 general & internal medicine ,anticoagulation ,risk scores ,Framingham Risk Score ,business.industry ,Anticoagulants ,Atrial fibrillation ,General Medicine ,North Africa ,medicine.disease ,Stroke ,Epidemiological transition ,Female ,Cardiology and Cardiovascular Medicine ,business ,management ,medicine.drug - Abstract
Background Contemporary registries on atrial fibrillation (AF) are scare in North African countries. Hypothesis In the context of the epidemiological transition, prevalence of valvular AF in Tunisia has decreased and the quality of management is still suboptimal. Methods NATURE‐AF is a prospective Tunisian registry, involving consecutive patients with AF from March 1, 2017 to May 31, 2017, with a one‐year follow‐up period. All the patients with an Electrocardiogram‐documented AF, confirmed in the year prior to enrolment were eligible. The epidemiological characteristics and outcomes were described. Results A total of 915 patients were included in this study, with a mean age of 64.3 ± 22 years and a male/female sex ratio of 0.93. Valvular AF was identified in 22.4% of the patients. The mean CHA2DS2VASC score in nonvalvular AF was 2.4 ± 1.6. Monotherapy with antiplatelet agents was prescribed for 13.8% of the patients. However, 21.7% of the subjects did not receive any antithrombotic agent. Oral anticoagulants were prescribed for half of the patients with a low embolic risk score. In 341 patients, the mean time in therapeutic range was 48.87 ± 28.69%. Amiodarone was the most common antiarrhythmic agent used (52.6%). During a 12‐month follow‐up period, 15 patients (1.64%) had thromboembolism, 53 patients (5.8%) had major hemorrhage, and 52 patients (5.7%) died. Conclusions NATURE‐AF has provided systematic collection of contemporary data regarding the epidemiological and clinical characteristics as well as the management of AF by cardiologists in Tunisia. Valvular AF is still prevalent and the quality of anticoagulation was suboptimal.
- Published
- 2021