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This study described the spatial distribution and trend of HIV/AIDS among older adults in China, and we tried to identify the clustering of infections and translocation of hotspots during the study period.Background. Recent studies have indicated an increasing burden of human immunodeficiency virus (HIV)/AIDS among older adults.Methods. All identified people living with HIV/AIDS (PLWHA) recorded through the Chinese HIV/AIDS CRS during 2005–2012 were included in the study, except for the cases that lacked specific spatial information. Trend tests and spatial analyses were conducted.Results. Information about 73,521 PLWHA (aged ≥50 years) was collected during 2005–2012. Three provinces—Guangxi, Henan, and Yunnan—accounted for 54.4% of the identified cases during the study period. Compared with 2005, the ratio between residents and migrants among the study population decreased to 40.1% in 2012. The ratio of HIV-infected patients to AIDS patients and the ratio of males to females increased gradually among older infected adults. Results of spatial analysis indicate a clustered distribution of HIV/AIDS among older adults throughout the country. Hot spots were observed in 4 provinces (Guangxi, Henan, Yunnan, and Sichuan) and 1 municipality (Chongqing). A trend from central provinces toward southern provinces was also identified.Conclusions. The number and proportion of HIV/AIDS among older adults have increased in recent years. The hot spots showed movement from central to southern China. A focused intervention strategy targeting the older PLWHA is urgently required in China. [ABSTRACT FROM AUTHOR]

This study described the prevalence and trend of HIV, hepatitis C virus (HCV) and syphilis among female sex workers (FSWs) in China, and we tried to identify the correlation between HIV, HCV and syphilis. Disparity of the epidemics were found between lower-tier and higher-tier FSWs.Background. Studies on the transmission of human immunodeficiency virus (HIV) and sexually transmitted diseases in female sex workers (FSWs) have been limited primarily to inferences drawn by focusing on defined geographical areas.Methods and Findings. This serial cross-sectional study was conducted in mainland China from 2008 through 2012. Data for 827 079 participants was analyzed. We classified venues such as karaoke bars and hotels as high tier and venues such as hair salons and barbershops, massage parlors, and other public outdoor venues as low tier based on the participants’ socioeconomic status. FSWs who worked at the venues and those who were present on the days of the survey were recruited.The prevalence of HIV decreased from 0.6% in 2008 to 0.3% in 2012, the syphilis prevalence ranged from 2.4% to 3.2% between 2008 and 2012, and hepatitis C virus (HCV) prevalence decreased from 0.9% in 2008 to 0.8% in 2012. Further, we found that HIV, syphilis, and HCV prevalence proportions were high in FSWs from low tiers.Conclusions. HIV, syphilis, and HCV prevalence among FSWs in our study decreased during the study period. Comprehensive intervention strategies, particularly those that focus on low-tier and older FSWs, are needed in order to decrease the disease burden in this population. [ABSTRACT FROM AUTHOR]