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12 results on '"Ullmann, Andrew"'

3. Comparison of 2 studies of treatment of invasive aspergillosis

Author

Denning, David W., Cornely, Oliver A., Maertens, Johan, Ullmann, Andrew J., Heussel, Claus Peter, and Herbrecht, Raoul

Subjects
Amphotericin B -- Dosage and administration, Aspergillosis -- Risk factors, Aspergillosis -- Development and progression, Aspergillosis -- Drug therapy, Drug therapy -- Comparative analysis, Health, Health care industry
Published
2007

4. Liposomal amphotericin B as initial therapy for invasive mold infection: a randomized trial comparing a high-loading dose regimen with standard dosing (AmBiLoad Trial)

Author

Cornely, Oliver A., Maertens, Johan, Bresnik, Mark, Ebrahimi, Ramin, Ullmann, Andrew J., Bouza, Emilio, Heussel, Claus Peter, Lortholary, Olivier, Rieger, Christina, Boehme, Angelika, Aoun, Mickael, Horst, Heinz-August, Thiebaut, Anne, Ruhnke, Markus, Reichert, Dietmar, Vianelli, Nicola, Krause, Stefan W., Olavarria, Eduardo, and Herbrecht, Raoul

Subjects
Amphotericin B -- Dosage and administration, Amphotericin B -- Research, Aspergillosis -- Care and treatment, Health, Health care industry
Published
2007

5. Safety of long-term oral posaconazole use in the treatment of refractory invasive fungal infections

Author

Raad, Issam I., Graybill, John R., Bustamante, Ana Beatriz, Cornely, Oliver A., Gaona-Flores, Veronica, Afif, Claude, Graham, Donald R., Greenberg, Richard N., Hadley, Susan, Langston, Amelia, Negroni, Ricardo, Perfect, John R., Pitisuttithum, Punnee, Restrepo, Angela, Schiller, Gary, Pedicone, Lisa, and Ullmann, Andrew J.

Subjects
Triazoles -- Dosage and administration, Triazoles -- Research, Mycoses -- Drug therapy, Neutropenia -- Drug therapy, Health, Health care industry
Published
2006

6. Early detection of Toxoplasma infection by molecular monitoring of Toxoplasma gondii in peripheral blood samples after allogeneic stem cell transplantation

Author

Martino, Rodrigo, Bretagne, Stephane, Einsele, Hermann, Maertens, Johan, Ullmann, Andrew J., Parody, Rocio, Schumacher, Ulrike, Pautas, Cecile, Theunissen, Koen, Schindel, Christine, Munoz, Carmen, Margall, Nuria, and Cordonnier, Catherine

Subjects
Toxoplasmosis -- Diagnosis, Toxoplasmosis -- Causes of, Hematopoietic stem cells -- Transplantation, Hematopoietic stem cells -- Complications and side effects, Health, Health care industry
Published
2005

9. Prospective Study of Amphotericin B Formulations in Immunocompromised Patients in 4 European Countries.

Author

Ullmann, Andrew J., Sanz, Miguel A., Tramarin, Andrea, Barnes, Rosemary A., Wu, Wenchen, Gerlach, Barbara A., Krobot, Karl J., and Gerth, William C.

Subjects
*AMPHOTERICIN B, *MEDICAL prescriptions, *ANTIFUNGAL agents, *ANTI-infective agents, *INTERNAL medicine, *IONOPHORES, *POLYENE antibiotics, *LENGTH of stay in hospitals
Abstract

Background. Amphotericin B is a widely used broad-spectrum antifungal agent, despite being associated with significant adverse events, including nephrotoxicity. Methods. The present prospective study collected data on outcomes for 418 adult patients treated consecutively with polyenes in hematology and oncology wards in 20 hospitals in Europe. Results. Patients initially received amphotericin B deoxycholate (62% of patients), liposomal amphotericin B (27%), or other lipid formulations of amphotericin B (11%). Of the patients initially treated with amphotericin B deoxycholate, 36% had therapy switched to lipid formulations of amphotericin B, primarily because of increased serum creatinine levels (in 45.7% of patients) or other amphotericin B-attributable adverse events (in 41.3% of patients). Nephrotoxicity, which was defined as a ⩾50% increase in the serum creatinine level, developed in 57% of patients with normal kidney function at baseline. Predictors of nephrotoxicity included formulation type and duration of treatment. Compared with patients without nephrotoxicity, patients with nephrotoxicity had a higher mortality rate (24%), and their mean length of stay in the hospital was prolonged by 8.6 days. Slight increases in the serum creatinine level (i.e., ⩾50%) were associated with a significantly longer stay in the hospital. Severe nephrotoxicity (i.e., a ⩾200% increase in the serum creatinine level) was a significant predictor of death, as were severe underlying medical conditions and documented fungal infection. Conclusion. This prospective study confirmed that, in European hospitals, amphotericin B formulations have a major influence on the length of stay in the hospital and nephrotoxicity-associated mortality. [ABSTRACT FROM AUTHOR]

Published
2006

10. Reply to Denning.

Author

Cornely, Oliver A., Maertens, Johan, Ullmann, Andrew J., Heussel, Claus Peter, and Herbrecht, Raoul

Subjects
LETTERS to the editor, ASPERGILLOSIS
Abstract

A response by O.A. Cornely to a letter to the editor about his article about the randomized study of invasive aspergillosis (IA) is presented.

Published
2007
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11. Hepatic Granuloma Due to Propionibacterium acnes in a Patient with Acute Myelogenous Leukemia.

Author

Ullmann, Andrew J., Helmreich-Becker, Ilka, Maeurer, Markus J., Han, Shan-Rui, Heussel, Claus P., Koehler, Heinz H., Fischer, Thomas, and Huber, Christoph

Subjects
*GRANULOMA, *CUTIBACTERIUM acnes, *LIVER disease diagnosis, *DIAGNOSIS
Abstract

Discusses a reported case of hepatic granulomatous infiltrates (HGI) due to Propionibacterium acnes (PA) in a 31-year-old woman with acute myelogenous leukemia. Isolation of pure PA growth from two different sterile sites; Identification of two identical nucleotide sequences of a PA gene in isolates from both the liver and bone marrow; Evidence that PA caused the HGI in the patient.

Published
2000
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