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A 49-year-old woman presented to the emergency room with subacute paraparesis associated with bilateral cervicobrachial neuralgia. Brain and spine MRI revealed a heterogeneous hypervascular pineal tumor and a multifocal thoracolumbar intradural-extramedullary infiltrate with signs of medullary compression. C7-T2 laminectomy was performed on the same day for medullary decompression, allowing for partial lesion excision. Histological examination was in favor of a poorly differentiated anaplastic ependymoma. Two weeks later, FDG-PET showed markedly increased uptake in the pineal mass and significant hypermetabolism of the spinal metastases.

Fasting 18F fluoro-deoxy-glucose positron emission tomography examinations are routinely performed for the staging of HIV-associated lymphomas. In addition to possible comorbidity factors, the chronic inflammation that occurs in HIV-infected patients together with the metabolic side effects of antiretroviral therapy increases the risk for coronary artery disease. Moreover, HIV-infected patients are likely to develop polyneuropathies due to the viral infection or to the side effects of long-term protease or nucleoside reverse transcription inhibitor treatments.We report a case that illustrates the need to suspect the diagnosis of silent myocardial ischemia among HIV-positive patients with myocardial F-18 fluoro-deoxy-glucose uptake involving a coronary artery territory.

Somatostatin receptor scintigraphy is habitually indicated in the evaluation of neuroendocrine tumors. We report the case of a 44-year-old woman with an unexpected vasculitis, which was detected on In-111 pentetreotide scintigraphy. Vascular uptake of the tracer was observed at presentation and disappeared after 3 months of corticotherapy.

We report a case of a 61-year-old man who underwent coronary artery bypass grafting in 1975 and progressively developed chronic sternal osteomyelitis. He was examined for fever with an increase of pain and swelling of thesternal scar. Computed tomographic scan performed 2 weeks before was normal. The patient was referred to the nuclear medicine department for a bone scan. There was a high level of blood-pool activity in the lower thorax in the blood-pool phase, and intense linear midline uptake was observed extending from the lower thorax into the upper abdomen in the late phase. Anterior and posterior Tc-99m HMPAO-labeled leukocyte images of the chest and abdomen obtained approximately 24 hours after injection demonstrated major accumulation in the same location extending to the anterior mediastinum. A control computed tomographic scan for comparison obtained 1 day later demonstrated a large retrosternal abscess with sternal osteomyelitis. This was confirmed at surgery with drainage of pus. Staphylococcus aureus was isolated. The patient was treated with appropriate antibiotics with good effect.